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Перегляд Вiopolymers and Cell, 2019, vol. 35 за датою випуску

Репозиторій DSpace/Manakin

Перегляд Вiopolymers and Cell, 2019, vol. 35 за датою випуску

Сортувати за: Порядок: Результатів:

  • Kropyvko, S.V.; Tsyba, L.O.; Novokhatska, O.V.; Nemesh, Y.M.; Syvak, L.A.; Tarasenko, T.Ye.; Grabovoy, A.N.; Rynditch, A.V. (Вiopolymers and Cell, 2019)
    Aim. Regardless a great progress in treatment, 15% of breast cancer cases remain lethal. One of the main problems in diagnosis and cure of this cancer type is its high clinical and genetic heterogeneity, and the identification ...
  • Popov, A.A.; Evdokimov, A.N.; Lukyanchikova, N.V.; Petruseva, I.O.; Lavrik, O.I. (Вiopolymers and Cell, 2019)
    In the previous studies, the DNA with the bulky Fap-dC derivative was demonstrated to be a difficult substrate for the nucleotide excision repair (NER), a system which is involved in the removal of bulky lesions from DNA. ...
  • Pushkarova, N.O.; Lakhneko, O.R.; Morgun, B.V.; Kuchuk, M.V.; Blume, Ya.B.; Yemets, A.I. (Вiopolymers and Cell, 2019)
    In vitro culture can be used for endangered species preservation but its effect on biochemical properties and genetic stability of plants requires further research. Aim. The study on fatty acids content, phenolic compounds ...
  • Semeniuk, D.O.; Starenka, I.O.; Pogribna, A.P.; Sokol, I.V.; Govsieiev, D.O. (Вiopolymers and Cell, 2019)
    Aim. To investigate an ability of HBD-2 to induce aggregation of erythrocytes. Methods. Aggregation assay, turbidimetry, light microscopy. Results. We have identified aggregation of erythrocytes in presence of at least ...
  • Antonyuk, V.O.; Skorohyd, N.R.; Lozynskyi, A.V.; Antonyuk, R.V.; Lesyk, R.B.; Stoika, R.S. (Вiopolymers and Cell, 2019)
    Aim.To determine cytotoxic effects towards a tumor cells culture of the heterocyclic derivative conjugated with lectins of different carbohydrate specificity. Methods. Conjugation of lectins (Pea seeds (PSA), peanuts (PNA) ...
  • Mishchenko, L.T.; Dunich, A.A.; Skrypkina, I.Ya.; Kozub, N.O. (Вiopolymers and Cell, 2019)
    The study of molecular characteristics and, in particular, the nucleotide (nt) and amino acid (aa) sequences of the viral genomes, is necessary to know the changes in their geographical range, phylogenetic relationships, ...
  • Tarnavskiy, S.S.; Protopopov, M.V.; Borovykov, O.V.; Pryhodko, A.O.; Bdzhola, V.G.; Yarmoluk, S.M. (Вiopolymers and Cell, 2019)
    Aim. To identify novel FGFR1 inhibitors using the virtual screening approach. Methods. Virtual screening of a small organic compounds library was performed by molecular docking using the Autodock 4.2.6 program package. The ...
  • Pankivskyi, S.V.; Senchenko, N.V.; Busko, P.B.; Rynditch, A.V. (Вiopolymers and Cell, 2019)
    Aim. To identify novel ITSN1 and ITSN2 partners among RNA-binding proteins (RBPs) involved in regulation of mRNA processing. Methods. GST pull-down, immunoprecipitation assays and bioinformatics analysis was used to identify ...
  • Gerush, I.V.; Ferenchuk, Ye.O. (Вiopolymers and Cell, 2019)
    There are different opinions about the role of hydrogen sulfide (H2S) in catalytic and energy processes, but the biochemistry of all possible effects of H2S is not well studied yet. The enzymatic synthesis of H2S is catalyzed ...
  • Matvieieva, A.S.; Kovalevska, L.M.; Ivanivska, T.S.; Klein, E.; Kashuba, E.V. (Вiopolymers and Cell, 2019)
    Aim. To find out the cause of inhibition of the IL2-STAT5 signaling pathway in chronic lymphocytic leukemia (CLL) cells. Methods.CLL cells were isolated from peripheral blood, using gradient centrifugation on a ficoll-verografin ...
  • Gerashchenko, G.V.; Grygoruk, O.V.; Rosenberg, E.E.; Bondarenko, Yu.M.; Kashuba, E.V.; Kashuba, V.I. (Вiopolymers and Cell, 2019)
    Aim. To analyze an expression pattern of the cancer-associated genes in prostate tumors at mRNA and protein levels and find putative association between the expression of these genes and the genes, controlling epithelial ...
  • Kotey, I.M.; Protopopov, M.V.; Starosyla, S.A.; Balanda, A.O.; Pletnova, L.V.; Prykhod'ko, A.O.; Bdzhola, V.G.; Yarmoluk, S.M. (Вiopolymers and Cell, 2019)
    Aim. To identify novel FGFR1 inhibitors using virtual screening approach. Methods. We used methods of organic synthesis, molecular docking via the Autodock 4.2.6 program package and in vitro biochemical tests with γ-32P. ...
  • Ryazanova, O.A.; Zozulya, V.N.; Voloshin, I.M.; Glamazda, A.Yu.; Dubey, I.Ya.; Dubey, L.V.; Karachevtsev, V.A. (Вiopolymers and Cell, 2019)
    Aim. To study the binding of a water-soluble cationic Pheophorbide-a derivative (CatPheo-a) ta a Na+–stabilized antiparallel quadruplex formed by 22-mer oligonucleotide d[AG3(T2AG3)3] of the human DNA telomeric sequence ...
  • Zaiets, I.V.; Holiar, V.V.; Filonenko, V.V. (Вiopolymers and Cell, 2019)
    Aim. To identify a splicing mRNA of S6K1 kinase specific for the p60-S6K1 isoform alone. Methods. RT-PCR, DNA sequencing, Western blotting. Results. RT-PCR analysis of total RNA extracted from MCF-7 cells and subsequent ...
  • Kutuzov, M.M.; Kurgina, T.A.; Belousova, E.A.; Khodyreva, S.N.; Lavrik, O.I. (Вiopolymers and Cell, 2019)
    Nucleosome core particles (NCPs) are basic units of chromatin organization; they represent the most convenient model system for the study of key DNA-dependent processes. Therefore, a robust method of nucleosome assembly ...

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