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Хімічні та біологічні науки
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Biopolymers and Cell
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Вiopolymers and Cell, 2016, vol. 32
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Вiopolymers and Cell, 2016, № 6
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Перегляд Вiopolymers and Cell, 2016, № 6 за датою випуску

Перегляд Вiopolymers and Cell, 2016, № 6 за датою випуску

Результати 1-7 з 7

Identification and characterization of six new mutations in GLB1 gene in Ukrainian patients with GM1 gangliosidosis and Morquio B disease

Mytsyk, N.Y.; Gorovenko, N.G. (Вiopolymers and Cell, 2016)

GM1-gangliosidosis (MIM# 230500) and mucopolysaccharidosis IV (Morquio B, MIM# 230500) are autosomal-recessive diseases, which belong to the group of lysosomal storage disorders and are caused by changes in the structure ...
Use of lectin as a vector molecule for delivery of medicinal products to cells and tissues

Antonyuk, V.O.; Klyuchivska, O.Yu.; Antonyuk, R.V.; Lozynskyi, A.V.; Pohranychna, Kh.R.; Lesyk, R.B.; Stoika, R.S. (Вiopolymers and Cell, 2016)

Aim. The conjugation of low-molecular compounds with antitumor activity to lectin and evaluation of the biological activity of the obtained conjugate. Methods. Organic synthesis; obtaining and analyzing Pisum sativum ...
Telomerase inhibition by new di- and trisubstituted acridine derivatives

Negrutska, V.V.; Saraieva, I.V.; Kostina, V.G.; Alexeeva, I.V.; Lysenko, N.A.; Dubey, I.Ya. (Вiopolymers and Cell, 2016)

Aim. To study a series of new acridine derivatives containing two basic fragments able to bind to quadruplex DNA at C-4 and C-9 positions as potential telomerase inhibitors. Methods. TRAP assay was used to determine the ...
A potential role of hydrogen sulfide (H₂S) in the regulation of the Ras-ERK signaling-dependent transcription of DNA methyltransferases

Nikitina, T.A. (Вiopolymers and Cell, 2016)

Ras-ERK cell signaling regulates transcription of DNA methyltransferases (DNMTs). A role of H₂S in regulation of the Ras-ERK signaling activity and DNMTs expression has also been shown. Here we propose a hypothesis that ...
Transcriptome-based identification of PDGFA as a candidate secreted biomarker for hepatocellular carcinoma

Chesnokov, M.S.; Krivtsova, O.M.; Skovorodnikova, P.A.; Makarova, A.S.; Kustova, I.F.; Logacheva, M.D.; Penin, A.A.; Klepikova, A.V.; Shavochkina, D.A.; Kudashkin, N.E.; Moroz, E.A.; Patyutko, Y.I.; Kotelnikova, E.A.; Lazarevich, N.L. (Вiopolymers and Cell, 2016)

Aim. Identification of candidate secreted biomarkers for hepatocellular carcinoma (HCC) diagnosis. Methods. Genes upregulated in HCC tissue and encoding secreted proteins were identified by RNA-seq. Gene expression changes ...
Mouse embryonic fibroblasts expressing IFNβ or IL-21 inhibit proliferation of melanoma cells in vitro

Vagyna, I.N.; Zaharuk, O.A.; Strokovska, L.I.; Vagyn, Y.V.; Kashuba, V.I. (Вiopolymers and Cell, 2016)

Aim. To study an influence of mouse embryonic fibroblasts (C57Fb) transduced with baculovirus vectors (BVs), encoding genes for murine Ifn-β or human IL21, on survival and proliferation of the malignant mouse melanoma cells ...
Molecular-genetic characterization of Ukrainian patients with mucopolysaccharidosis I: identification of three new mutations in α-L-iduronidase gene

Trofimova, N.S.; Olkhovich, N.V. (Вiopolymers and Cell, 2016)

Mucopolysaccharidosis I (MPS I) is a rare hereditary autosomal-recessive metabolic disorder, which occurs due to the deficiency of the lysosomal enzyme α-L-iduronidase (IDUA; EC 3.2.1.76). There are three clinical forms ...

Результати 1-7 з 7

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Перегляд Вiopolymers and Cell, 2016, № 6 за датою випуску

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Перегляд Вiopolymers and Cell, 2016, № 6 за датою випуску

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