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Перегляд Вiopolymers and Cell, 2014, № 1 за датою випуску

Репозиторій DSpace/Manakin

Перегляд Вiopolymers and Cell, 2014, № 1 за датою випуску

Сортувати за: Порядок: Результатів:

  • Growth suppression activity of bradykinin antagonists in glioma cells 
    Avdieiev, S.S.; Gera, L.; Hodges, R.; Vassetzky, Y.S.; Kavsan, V.M. (Вiopolymers and Cell, 2014)
    The present study was Aimed at analyzing the effect of bradykinin (BK) antagonists on proliferation of the human glioblastoma cells U373. Methods. MTT-based cell proliferation assay. Results. BKM-570 revealed a significant ...
  • DNA import competence and mitochondrial genetics 
    Weber-Lotfi, F.; Mileshina, D.V.; Ibrahim, N.; Koulintchenko, M.V.; D'Souza, G.; Saxena, V.; Konstantinov, Yu.M.; Lightowlers, R.N.; Dietrich, A. (Вiopolymers and Cell, 2014)
    Aim. To understand the mechanism(s) underlying mitochondrial competence for DNA uptake and to exploit these pathways for the development of in vivo models of gene therapy. Methods. DNA uptake into isolated mitochondria ...
  • Ca/calmodulin-dependent phosphorylation of endocytic scaffold ITSN1 
    Morderer, D.Ye.; Nikolaienko, O.V.; Skrypkina, I.Ya.; Rymarenko, O.V.; Kropyvko, S.V.; Tsyba, L.O.; Rynditch, A.V. (Вiopolymers and Cell, 2014)
    ITSN1 is an endocytic scaffold protein with a prominent function in synaptic transmission. It is known that Ca signaling is crucial for the regulation of synaptic proteins functioning. Aim. Checking the possibility of ...
  • In memoriam: Victor I. Danilov (1936-2014) 
    Frank-Kamenetskii, M. (Вiopolymers and Cell, 2014)
  • Epigenetics: What it is about? 
    Saade, E.; Ogryzko, V.V. (Вiopolymers and Cell, 2014)
    Epigenetics has captured the attention of scientists in the past decades, yet its scope has been continuously changing. In this paper, we give an overview on how and why its definition has evolved and suggest several ...
  • Phylogenetic study on structural elements of HIV-1 poly(A) region. 2. USE domain and TAR hairpin 
    Zarudnaya, M.I.; Potyahaylo, A.L.; Kolomiets, I.M.; Hovorun, D.M. (Вiopolymers and Cell, 2014)
    Aim Phylogenetic study on structural elements in the poly(A) region of human immunodeficiency virus type 1 (HIV-1), in particular the major upstream sequence element (USE), which stimulates polyadenylation of HIV-1 transcript, ...
  • Structure and function of oncogene-transfected immortal cells 
    Kavsan, V.M.; Kulagova, T.A.; Kuznetsova, T.A.; Semenkova, G.N.; Stepanenko, A.A.; Vassetzky, Y.S. (Вiopolymers and Cell, 2014)
    Previously we have characterized a new oncogene CHI3L1, overexpressed in the glioblastoma and the malignant 293_CHI3L1 cells, stably producing the CHI3L1 angiogenic oncoprotein. The 293_CHI3L1 cells proliferated faster and ...
  • The start of systems biology in Ukraine 
    Obolenskaya, M.Yu.; Tokovenko, B.T.; Kuklin, A.V.; Frolova, A.A.; Rodriguez, R.R.; Dotsenko, V.A.; Dragushchenko, O.O. (Вiopolymers and Cell, 2014)
    The first laboratory of Systems Biology in Ukraine (IMBIG NASU) represents a track record of its scientific results. They include the pioneered development of a web-based tool for genome-wide surveys of eukaryotic promoters ...
  • Novel aspects of platelet aggregation 
    Roka-Moya, Y.M.; Bilous, V.L.; Zhernossekov, D.D.; Grinenko, T.V. (Вiopolymers and Cell, 2014)
    The platelet aggregation is an important process, which is critical for the hemostatic plug formation and thrombosis. Recent studies have shown that the platelet aggregation is more complex and dynamic than it was previously ...
  • Effect of anticancer drugs on breast cancer cells sensitive and resistant to doxorubicin: expression of mRNAs of TGF-β and its receptors 
    Chorna, I.V.; Fedorenko, O.V.; Stoika, R.S. (Вiopolymers and Cell, 2014)
    Aim. Comparative study of the effect of chemotherapeutic drugs (doxorubicin, methotrexate and cisplatin) and TGF-β on the human breast carcinoma MCF-7 cells, sensitive (wt) and resistant (DOX/R) to the doxorubicin action. ...
  • Suppression of tumorigenicity and metastatic potential of melanoma cells by transduction of interferon gene 
    Lykhova, A.A.; Kudryavets, Yu.I.; Bezdenezhnykh, N.A.; Semesiuk, N.I.; Adamenko, I.N.; Vorontsova, A.L. (Вiopolymers and Cell, 2014)
    The aim of this study was to investigate an inhibitory effect of baculovirus-mediated transduction of the murine interferon-beta gene on mouse melanoma in vitro and in vivo. Methods. Studies were performed on B16 mouse ...
  • T-138C polymorphism of MGP gene is associated with blood plasma cholesterol levels but not related to other risk factors of atherosclerosis in patients with ischemic stroke 
    Garbuzova, V.Yu.; Polonikov, A.V.; Ataman, Y.A.; Mychaylova, T.I.; Obukhova, O.A.; Matlaj, O.I.; Ataman, A.V. (Вiopolymers and Cell, 2014)
    Aim. To analyse the association of MGP gene promotor T-138C polymorphism (rs1800802) with known risk factors of atherosclerosis and its complications (hypercholesterolemia, hypertension, high body mass index, diabetes, ...
  • Ku80 interaction with apurinic/apyrimidinic sites depends on the structure of DNA ends 
    Kosova, A.A.; Khodyreva, S.N.; Lavrik, O.I. (Вiopolymers and Cell, 2014)
    Aim. The identification of a protein from human cell extract which specifically interacts with the apurinic/apyrimidinic (AP) site in the partial DNA duplex containing 5'and 3'-dangling ends (DDE-AP DNA) and mimicking ...
  • Interaction between adaptor proteins Ruk/CIN85 and Tks4 in normal and tumor cells of different tissue origins 
    Bazalii, A.V.; Samoylenko, A.A.; Petukhov, D.M.; Rynditch, A.V.; Redowicz, M.-J.; Drobot, L.B. (Вiopolymers and Cell, 2014)
    Aim. To study the interaction of adaptor protein Ruk/CIN85 SH3 domains with endogenous adaptor protein Tks4 in normal and tumor cells of different tissue origins. Methods. GST in vitro pull-down assay was performed using ...
  • Specificity of DNA import into isolated mitochondria from plants and mammals 
    Koulintchenko, M.V.; Ibrahim, N.; Klimenko, E.S.; Konstantinov, Yu.M.; Weber-Lotfi, F.; Dietrich, A. (Вiopolymers and Cell, 2014)
    Aim. Investigation of different features of DNA import into plant and human mitochondria, for a better understanding of mitochondrial genetics and generation of biotechnological tools. Methods. DNA up-take experiments with ...

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