Роль α-токоферола и N-ацетил-L-цистеина в оксидативном стрессе, индуцированном менадионом

Abstract

It is established that α-tocopherol does not play the main role in the protection of rat thymo-cytes from damaging by menadione - generated superoxide that calls into question its ability to prevent oxidative stress. Efficiency of a predecessor of the glutatione synthesis, N-acetyl-L-cysteine, in the given model testifies to involving other antioxidative protection systems in this process.