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періодичних видань НАН України
Rat xenograft chondrosarcoma development by human tissue fragment
Репозиторій DSpace/Manakin
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Rat xenograft chondrosarcoma development by human tissue fragment
Тема:
Short communications
Посилання:
Rat xenograft chondrosarcoma development by human tissue fragment / M. Hemmati, A. Abbaspour, A.M. Alizadeh, M. Khaniki, A. Amanzadeh, M.A. Mohagheghi, M.S. Mousavi // Experimental Oncology. — 2011. — Т. 33, № 1. — С. 52–54. — Біліогр.: 16 назв. — англ.
Підтримка:
The present research was supported by Tehran University of Medical Sciences and health services, a grant of Cancer Research Center of Emam Khomeini Hospital. We thank Dr. Faezipour for handling the patient in the operation room in Cancer Research Center of Cancer Institute. Also, we thank Dr. Akbari for histopathological consultance in the Department of Pathology, Baghiyatallah Hospital.
Дата:
2011
Переглядів:
1525
Завантажень:
938
Анотація:
Aim: We conducted this study to develop a chondrosarcoma on rat by graft of human chondrosarcoma tumor tissue. Methods: Fourteen male Sprague-Dawley rats equally divided in xenograft-implanted and control groups. On the lateral side of the right femur distal 1/3, 5 mm incision was done on the skin after animal anesthesia. Then, was drilled 3 mm on the bone and implanted the xenograft in the bone. Radiography was taken from the operated femur weekly until the fourth week and monthly for 3 months. Four animals of each group were sacrificed after 4 weeks of operation; femur was harvested for histopathological study.
