Перегляд Biopolymers and Cell за темою "Reviews"

Сортувати за: Порядок: Результатів:

  • 2'-5'-Oligoadenylates as a «tool» of innate immunity 
    Tkachuk, Z.Yu. (Вiopolymers and Cell, 2013)
    It is a matter of common knowledge, that «core» 2'-5'-oligoadenylates and their analogues posses broader biological activity than it can be predicted within the traditional «interferon» hypothesis. They exhibit immunomodulatory ...
  • 2D- and 3D-cell culture 
    Khoruzhenko, A. I. (Вiopolymers and Cell, 2011)
    The cultivation of mammalian cells in three-dimensional conditions acquires a priority in a variety of biomedical applications. In the areas of toxicology and anticancer drug development it concerns a significant difference ...
  • 40 years within two epochs of two millennia 
    Kordium, V.A. (Вiopolymers and Cell, 2013)
    The article-generalization deals with the main directions being developed in the Department of Cell Regulatory Mechanisms during past 40 years from the moment of the Institute of Molecular Biology and Genetics of Academy ...
  • Aberrant DNA glycosylase-initiated repair pathway of free radicals in-duced DNA damage: implications for age-related diseases and natural aging 
    Matkarimov, B.T.; Saparbaev, M.K. (Вiopolymers and Cell, 2017)
    Aerobic cellular respiration generates reactive oxygen species (ROS), which can damage macro-molecules including lipids, proteins and DNA. It was proposed that aging is a consequence of accumulation of naturally occurring ...
  • Allelic polymorphism of glucocorticoid receptor NR3C1 (GR): from molecular biology to clinical implications 
    Orlovsky, M.A. (Вiopolymers and Cell, 2012)
    Polymorphism of stress-related genes is a key factor determining difference in the stress reactivity and resistance among humans. Glucocorticoid receptors are important actors of stress responses. This review is focused ...
  • A potential role of hydrogen sulfide (H₂S) in the regulation of the Ras-ERK signaling-dependent transcription of DNA methyltransferases 
    Nikitina, T.A. (Вiopolymers and Cell, 2016)
    Ras-ERK cell signaling regulates transcription of DNA methyltransferases (DNMTs). A role of H₂S in regulation of the Ras-ERK signaling activity and DNMTs expression has also been shown. Here we propose a hypothesis that ...
  • A review on microcephaly genes 
    Shahid, S.; Irshad, S. (Вiopolymers and Cell, 2012)
    В обзоре обобщены данные последних лет по изучению генов микроцефалии. Обсуждаются результаты молекулярно-генетического исследования этих генов, сделана оценка семи определенных локусов (MCPH1–MCPH7), описаны соответствующие ...
  • Baculovirus vectors in experimental geneand vaccine therapy 
    Solomko, A.P.; Zaharuk, O.A.; Chaschina, L.I.; Strokovskaya, L.I. (Вiopolymers and Cell, 2011)
    The article provides a brief overview of the literature on target design, exploration properties and effectiveness of the application of recombinant baculoviruses in model systems in vivo. The results of experiments with ...
  • Biosensors. A quarter of a century of R&D experience 
    Soldatkin, A.P.; Dzyadevych, S.V.; Korpan, Y.I.; Sergeyeva, T.A.; Arkhypova, V.N.; Biloivan, O.A.; Soldatkin, O.O.; Shkotova, L.V.; Zinchenko, O.A.; Peshkova, V.M.; Saiapina, O.Y.; Marchenko, S.V.; El'skaya, A.V. (Вiopolymers and Cell, 2013)
    The paper is a review of the researches of Biomolecular Electronics Laboratory concerning the development of biosensors based on electrochemical transducers (amperometric and conductometric electrodes, potentiometric ...
  • Cancer–stroma interactions as a target for cancer treatment. 
    Alekseenko, I.V.; Pleshkan, V.V.; Sverdlov, E.D. (Інститут молекулярної біології і генетики НАН УкраїниВiopolymers and Cell, 2018)
    During tumor evolution, cancer cells use the tumor-stroma crosstalk to reorganize the microenvironment for maximum robustness of tumor. The success of immune checkpoint therapy generates a new cancer therapy paradigm: an ...
  • Cardiovascular disease risk factors for women. A life course-events perspective 
    Hobel, C.J.; Arora Chander, P. (Вiopolymers and Cell, 2010)
    Cardiovascular disease (CVD) in women is the most common cause of death and in 2009 accounted for one third of all deaths. The purpose of this paper is to present what conditions during pregnancy and during the pre-menopause ...
  • Cell cycle and epigenetic changes of plant DNA 
    Shevchenko, G.V. (Вiopolymers and Cell, 2010)
    Plants can apply various strategies to minimize environmental impact. One of the strategies is heritable modifications of gene expression which occur without changing original DNA sequence and are known as epigenetic. ...
  • Characteristic of mTOR signaling and its involvement in the regulation of cell movements through remodeling the cytoskeleton architecture 
    Kosach, V.R.; Cherednyk, O.V.; Khoruzhenko, A.I. (2015)
    mTOR kinase is one of the basic links at the crossroad of several signal transduction pathways. De­re­gulated mTOR kinase signaling accompanies the progress of cancer, diabetes, neurodegenerative disorders and aging. ...
  • Chitosan-apatite composites: synthesis and properties 
    Sukhodub, L.F.; Sukhodub, L.B.; Chorna, I.V. (Вiopolymers and Cell, 2016)
    The aim of this short review was to discuss applications of a unique biopolymer chitosan in practical medicine, especially for bone tissue engineering. The article highlights the preparation and properties of innovative ...
  • C-methods to study 3D organization of the eukaryotic genome 
    Gavrilov, A.A.; Razin, S.V.; Iarovaia, O.V. (Вiopolymers and Cell, 2012)
    В последнее время становится все более очевидным, что пространственная организация эукариотического генома играет важную роль в регуляции экспрессии генов. Трехмерную (3D) организацию генома можно исследовать с помощью ...
  • Control of the amount and functionality of the eEF1A1 and eEF1A2 isoforms in mammalian cells 
    Negrutskii, B.S.; Novosylna, O.V.; Porubleva, L.V.; Vislovukh, A.A. (Вiopolymers and Cell, 2018)
    Aim. To review mechanisms of regulation of expression and the functionality of two isoforms of translation elongation factor eEF1A in mammalian cells. Results. eEF1A1 and eEF1A2 proteins are regulated by post-translational ...
  • CRISPR/Cas9 technology for targeted genome editing 
    Lomov, N.A.; Borunova, V.V.; Rubtsov, M.A. (Вiopolymers and Cell, 2015)
    CRISPRs (Clustered Regularly Interspaced Short Palindromic Repeats) are the segments of prokaryotic DNA containing short repeats in its nucleotide sequence. Today we know that this is a bacterial protection system against ...
  • Crosstalk between endophytes and a plant host within information-processing networks 
    Kozyrovska, N.O. (Вiopolymers and Cell, 2013)
    Plants are heavily populated by pro- and eukaryotic microorganisms and represent therefore the tremendous complexity as a biological system. This system exists as an information-processing entity with rather complex processes ...
  • Current approaches to improve the anticancer chemotherapy with alkylating agents: state of the problem in world and Ukraine 
    Iatsyshyna, A.P. (Вiopolymers and Cell, 2012)
    Alkylating agents are frequently used in many established anticancer chemotherapies. They alkylate the genomic DNA at various sites. Alkylation of the guanine at the O6-position is cytotoxic, it has the strongest mutagenic ...
  • Current scenario on computer-aided metalloenzymes designing 
    Chellapandi, P. (Вiopolymers and Cell, 2011)
    The metalloenzymes are proteins with enzymatic activity which contain metals tightly bound in their active sites to display a chemical action. This review describes the recent developments and success of using ...

Пошук


Розширений пошук

Перегляд

Мій обліковий запис