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Experimental Oncology, 2018 (том 40)
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Перегляд Experimental Oncology, 2018 (том 40) за датою випуску

Перегляд Experimental Oncology, 2018 (том 40) за датою випуску

Результати 1-20 з 49

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Characterization of the cytotoxic effects of the combination of cisplatin and flavanol (-)-epicatechin on human lung cancer cell line A549. An isobolographic approach

Varela-Castillo, O.; Cordero, P.; Gutiérrez-Iglesias, G.; Palma, I.; Rubio-Gayosso, I.; Meaney, E.; Ramirez-Sanchez, I.; Villarreal, F.; Ceballos, G.; Nájera, N. (Experimental Oncology, 2018)

Background: Among malignancies, lung cancer is a leading cause of death. Platinum-based therapeutic compounds used to treat lung cancer have not been able to increase the survival of patients and such compounds have a high ...
Mediastinal yolk sac tumor infiltrating the heart

Imaniar, R.; Syahruddin, E.; Soepandi, P.Z.; Putra, A.C.; Nurwidya, F. (Experimental Oncology, 2018)

Background: As a rare tumor, yolk sac tumor is a type of neoplasm that appears like the yolk sac, extraembryonic mesenchyme, and allantois. The mediastinum is the second most frequent area after the gonadal area. Case ...
Molecular-genetic models for prognosis of development of tumors of reproductive system in women with family history of cancer

Paliychuk, O.V.; Polishchuk, L.Z.; Rossokha, Z.I.; Chekhun, V.F. (Experimental Oncology, 2018)

Aim: To develop a prognostic molecular genetic model for assessing the risk of development of benign and malignant tumors of female reproductive organs (FRO) in patients from cancer-affected families. Patients and Methods: ...
Morphological features of doxorubicin-resistant Walker 256 carcinosarcoma and response of mast cells

Boroday, N.V.; Chekhun, V.F. (Experimental Oncology, 2018)

Background: The mechanisms of drug resistance of cancer have not been yet elucidated in details. Recently, the role of mast cells (MCs) in the development of drug resistance has been brought in the limelight. The aim of ...
Highly activated carbon enterosorbent mediates the suppression of paraneoplastic syndrome associated with lewis lung carcinoma in mice

Sarnatskaya, V.V.; Sakhno, L.A.; Paziuk, L.M.; Yushko, L.A.; Rodionova, N.K.; Maslenny, V.N.; Sydorenko, A.S.; Nikolaev, V.G. (Experimental Oncology, 2018)

Aim: To investigate the effect of enterosorption on the development of paraneoplastic syndrome in mice with Lewis lung carcinoma (LLC). Materials and Methods: The study was performed on male С57/ВL6 mice with transplanted ...
Signatures of anti-Thomsen — friedenreich antigen antibody diversity in colon cancer patients

Kurtenkov, O.; Bubina, M.; Klaamas, K. (Experimental Oncology, 2018)

Aim: To determine whether the structural and functional diversities of naturally occurring antibodies to the Thomsen — Friedenreich (TF) antigen may be of diagnostic and prognostic value in colon cancer. Materials and ...
Sensitivity to 4-hydroxyestradiol and dna repair efficiency in peripheral blood lymphocytes of endometrial cancer patients

Buchynska, L.G.; Brieieva, O.V. (Experimental Oncology, 2018)

Background: The development of hormone-dependent cancers, including endometrial carcinomas, in great part may be mediated by the genotoxic effects of estrogen metabolites, among which 4-hydroxyestradiol (4OHE2) is characterized ...
Variant of rare hermansky — pudlak syndrome associated with granulomatous colitis: diagnostics, clinical course and treatment

Lozynska, L.Y.; Plawski, A.; Lozynska, M.R.; Vytvytskyi, I.; Lozynskyi, R.Y.; Prokopchuk, N.; Tretiak, B. (Experimental Oncology, 2018)

Aim: To study the relationship between the genotype and the phenotype in the patients with Hermansky — Pudlak syndrome (HPS) associated with granulomatous colitis; to monitor clinical course of the disease for adequate ...
Impact of endostatin gene therapy on myeloid-derived suppressor cells from a metastatic renal cell carcinoma

Chaves, K.C.B.; Costa, E.M.; Teixeira, L.F.; Bellini, M.H. (Experimental Oncology, 2018)

Aim: To evaluate the role of endostatin (ES) gene therapy on myeloid-derived suppressor cells (MDSC) in a metastatic model of renal cell carcinoma (RCC). Materials and Methods: Balb/C mice bearing orthotopic Renca tumors ...
A long survival of a patient with brain metastasis of unknown site of the primary tumor

Ben Kridis, W.; Sghaier, S.; Toumi, N.; Boudawara, Z.; Khanfir, A.; Daoud, J.; Frikha, M. (Experimental Oncology, 2018)

Eighty percent of brain metastases (BM) are diagnosed in patients with known primary site of cancer. BM of unknown primary represents a difficult diagnosis. In up to 15% of patients with BM, the site of the primary tumor ...
Role of components of microRNA machinery in carcinogenesis

Kian, R.; Moradi, S.; Ghorbian, S. (Experimental Oncology, 2018)

MicroRNAs (miRNAs) are a broad class of non-coding RNAs nearly 21 nucleotides length, which play crucial functions in posttranscriptional gene regulation. These molecules are associated with many developmental and cellular ...
Symposium and Summer School “Fundamental principles of cancer biotherapy” Kyiv, Ukraine, May 21-24, 2018

Автор відсутній (Experimental Oncology, 2018)
Effect of cytostatic agents on expression levels of human beta-defensins-1-4 in A431 and MCF-7 cell lines

Zubenko, O.S.; Semeniuk, D.O.; Starenka, I.O.; Pogribnyy, P.V. (Experimental Oncology, 2018)

The aim of the study was to analyze an effect of cytostatic agents of different mechanism of action on expression levels of human beta-defensins-1-4 (hBD-1-4) in cultured human cancer cell lines. Materials and Methods: ...
Increased homocysteine plasma levels in breast cancer patients of a Mexican population

Varela Almanza, K.M.; Puebla-Pérez, A.M.; Delgado-Saucedo, J.I.; Rodríguez-Arévalo, F.; Zúñiga-González, G.M.; Figuera, L.E.; Morán-Mendoza, A.; Gallegos-Arreola, M.P. (Experimental Oncology, 2018)

Aim: Hyperhomocysteinemia has been associated with different pathologies, including cardiovascular diseases, hypertension, diabetes, and breast cancer (BC). To examine the differences in total homocysteine (tHcy) plasma ...
Lymphocyte count in peripheral blood is a sensitive tool in pretreatment assessment of patients with urological cancer

Yakovlev, P.; Klyushin, D. (Experimental Oncology, 2018)

Cancer, inflammation and immune surveillance recruit lymphocytes as common key cellular players. The aim of the study was to assess a utility of the absolute and relative lymphocyte counts (ALC and RLC) in peripheral blood ...
Anagrelide and the CALR mutation allele burden in essential thrombocythemia

Atkinson, E.; Bakri, M.; Hayat, A.; Langabeer, S.E. (Experimental Oncology, 2018)
Clinical and immunohistochemical features of primary breast cancer and metachronous ovarian and endometrial tumors

Kryzhanivska, A.E.; Dyakiv, I.B.; Kyshakevych, I. (Experimental Oncology, 2018)

The aim of the study was to assess the patterns of development of metachronous cancer (endometrial cancer, EC, and ovarian cancer, OC) in breast cancer (BC) patients dependent of receptor phenotype of breast tumors. Materials ...
Materials of symposium and summer school “Fundamental Principles of Cancer Biotherapy”, May 21–23, 2018, Kyiv, Ukraine

Автор відсутній (Experimental Oncology, 2018)

The International Scientific Symposium “Fundamental Principles of Cancer Biotherapy” was held on May 21–23, 2018 in Kyiv, Ukraine. It was organized by R.E. Kavetsky Institute of Experimental Pathology, Oncology and ...
Differentiated thyroid carcinomas associated with chronic thyroiditis: biological and clinical properties

Myshunina, T.M.; Guda, B.D.; Bolgov, M.Yu.; Mikhailenko, N.I.; Tronko, N.D. (Experimental Oncology, 2018)

Aim: To determine biological and clinical features of papillary and follicular thyroid carcinomas associated or not associated with chronic thyroiditis. Materials and Methods: The study was conducted by retrospective ...
Clinical implications of p53 alterations in oral cancer progression: a review from India

Patel, K.R.; Vajaria, B.N.; Singh, R.D.; Begum, R.; Patel, P.S. (Experimental Oncology, 2018)

p53 plays a central role in prevention of normal cell from the development of the malignant phenotype. Somatic alterations (mutations, loss of heterozygosity, deletions) in p53 are a hallmark of most human cancers and cause ...

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Перегляд Experimental Oncology, 2018 (том 40) за датою випуску

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