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Experimental Oncology, 2013 (том 35)
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Перегляд Experimental Oncology, 2013 (том 35) за датою випуску

Перегляд Experimental Oncology, 2013 (том 35) за датою випуску

Результати 1-20 з 62

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Fractionated low-dose radiation exposure potentiates proliferation of implanted tumor cells

Gerashchenko, B.I.; Ryabchenko, N.M.; Glavin, O.A.; Rodionova, N.K.; Makovetska, L.I.; Ganzha, O.B.; Druzhyna, M.O.; Mikhailenko, V.M. (Experimental Oncology, 2013)

Aim: The purpose of this study is to test whether whole-body fractionated exposure of tumor-free animals to low doses of low-LET radiation (at the total delivered dose of 1.0 Gy of X-rays) is capable of potentiating growth ...
Cloning of variable fragments of tumor immunoglobulin, assembling and expressing of human SCFV protein in E. coli for anti-idiotype vaccination

Meleshko, A.N.; Vashkevich, K.P.; Fomina, E.G.; Scheslenok, E.P.; Schkolina, T.V.; Sergeev, G.V. (Experimental Oncology, 2013)

Aim: Idiotype, the unique part of immunoglobulin molecule expressed on the surface of B-cells, represents a specific antigen for vaccination against lymphoma. We have developed a rapid method for immunoglobulin variable ...
Influence of polychemotherapy on the morphology of metastases and kidney of resistant RLS-bearing mice

Zonov, E.V.; Voronina, E.I.; Zenkova, M.A.; Ageeva, T.A.; Ryabchikova, E.I. (Experimental Oncology, 2013)

Aim: Polychemotherapy (PCT), widely used for the antitumor treatment has a pronounced toxic effect on the organism, and its cytostatic effect sometimes is canceled by multidrug resistance of a neoplasia. Comprehension of ...
Search for potential gastric cancer markers using miRNA databases and gene expression analysis

Volkomorov, V.; Grigoryeva, E.; Krasnov, G.; Litviakov, N.; Tsyganov, M.; Karbyshev, M.; Zavyalova, M.; Afanasyev, S.; Cherdyntseva, N.; Lisitsyn, N.; Beresten, S. (Experimental Oncology, 2013)

Aim: The aim of this study was to identify genes that are differentially expressed in gastric tumors and to analyze the association of their expression level with tumor clinicopathologic features. Methods: In the present ...
Impact of dihydropyrrol derivative on the normal colonic mucosa of DMH-induced colon cancer rats compared with 5-fluorouracil

Kuznietsova, H.M.; Ogloblya, O.V.; Ryabchenko, V.K. (Experimental Oncology, 2013)

Aim: To compare the effects of cytostatic compound dihydropyrrol derivative (D1, 5-amyno-4-(1,3-benzothyazol-2-yl)-1-(3-methoxyphenyl)-1,2-dihydro-3Н-pyrrol-3-one) and 5-fluorouracil (5-FU) on the normal colonic mucosa of ...
In vitro modification of cisplatin cytotoxicity with magnetic fluid

Chekhun, V.F.; Yurchenko, O.V.; Naleskina, L.A.; Demash, D.V.; Lukianova, N.Yu.; Lozovska, Yu.V. (Experimental Oncology, 2013)

Aim: To study cytotoxicity of cisplatin conjugated with magnetic fluid (nanocomposite) upon exposure to magnetic field on sensitive and resistant to cisplatin MCF-7 human breast cancer cells. Methods: Cytotoxic activity ...
Immunohistochemical evaluation of p53 expression in lung cancer of patients with paraneoplastic rheumatic syndrome

Lysenko, S.A. (Experimental Oncology, 2013)

Aim: To study p53 expression in the tumor tissue of lung cancer (LC) patients with paraneoplastic rheumatic syndrome (PNRS). Materials and Methods: There have been used either biopsy or surgically resected tumor samples ...
Activity of thymidilate «salvage pathway» enzymes in human gastric cancer and blood serum: correlation with treatment modalities

Borzenko, B.G.; Bakurova, E.M.; Popovich, Yu.A.; Sidyuk, E.A.; Popovich, A.Y. (Experimental Oncology, 2013)

A comparative study of enzyme activity features of thymidilate “salvage pathway” synthesis in blood serum and tissues of different age patients with gastric cancer (T3–4N0-xM0) was carried out. Aim: To evaluate the diagnostic ...
Experimental validation of prevention of the development of stochastic effects of low doses of ionizing radiation based on the analysis of human lymphocytes’ chromosome aberrations

Domina, E.A.; Chekhun, V.F. (Experimental Oncology, 2013)

Aim: On the basis of the cytogenetic research, to develop and validate the strategy of the measures to prevent the stochastic effects of low-doses radiation on humans. Methods: Test system with human peripheral blood ...
Endoscopic method of intestinal decompression with the use of entero- and colonosorption in treatment of rectal cancer complicated with intestinal obstruction

Kalinin, O.E. (Experimental Oncology, 2013)

The treatment of rectal cancer patients with large bowel obstruction (LBO) is a serious health care problem. That’s why we have studied a possibility of conservative LBO treatment by the method of endoscopic recanalization. ...
Enterosorption as a method to decrease the systemic toxicity of cisplatin

Sakhno, L.A.; Yurchenko, O.V.; Maslenniy, V.N.; Bardakhivskaya, K.I.; Nikolaeva, V.V.; Ivanyuk, A.A.; Shevchuk, O.O.; Korotich, V.G.; Nikolaev, V.G. (Experimental Oncology, 2013)

A perspective adsorptive method to minimize systemic toxic effects of chemotherapy is enterosorption (ES). However, the capabilities of this method are far from being completely studied. The question remains opened — should ...
Repression of matrix metalloproteinases and inhibition of cell invasion by a nutrient mixture, containing ascorbic acid, lysine, proline, and green tea extract on human fanconi anemia fibroblast cell lines

Roomi, M.W.; Roomi, N.W.; Bhanap, B.; Niedzwiecki, A.; Rath, M. (Experimental Oncology, 2013)

Aim: Fanconi Anemia, an autosomal recessive disorder, is characterized by chromosomal abnormality leading to birth defects, progressive bone marrow failure, and a high probability of developing malignancy at an early age. ...
Nitric oxide coordinates development of genomic instability in realization of combined effect with ionizing radiation

Mikhailenko, V.M.; Diomina, E.A.; Muzalov, I.I.; Gerashchenko, B.I. (Experimental Oncology, 2013)

The aim of this study was to investigate the ability of environmental nitrogen oxides or natural nitric oxide (NO) donors to modify free radicals balance and development of genomic instability alone or in combination with ...
Recurrence of borderline ovarian tumors

Svintsitskiy, V.S.; Vorobyova, L.I.; Klymenko, E.S.; Dermenzhy, T.V.; Tkalya, J.G. (Experimental Oncology, 2013)

Aim - to increase the efficiency of diagnosis and treatment of patients with recurrences of borderline ovarian tumors (BOT). 106 patients with BOT of stage I have been treated and clinically observed: the I group (82 ...
Ukrain and its emerging role as an antineoplastic agent in systemic malignancies

Kapoor S. (Experimental Oncology, 2013)
The second Ukrainian-Swedish workshop "Translational oncology: old and new paradigms”

Автор відсутній (Experimental Oncology, 2013)
Tumor cell heterogeneity

Chekhun, V.F.; Sherban, S.D.; Savtsova, Z.D. (Experimental Oncology, 2013)

The paper deals with the analysis of literary data on the tumor cell heterogeneity. Phenotypic, genetic and epigenetic mechanisms of heterogeneity are considered. The heterogeneity or metastasis is considered too. The ...
Biologic activities of recombinant human-beta-defensin-4 toward cultured human cancer cells

Gerashchenko, O.L.; Zhuravel, E.V.; Skachkova, O.V.; Khranovska, N.N.; Filonenko, V.V.; Pogrebnoy, P.V.; Soldatkina, M.A. (Experimental Oncology, 2013)

Aim - the aim of the study was in vitro analysis of biological activity of recombinant human beta-defensin-4 (rec-hBD-4). Methods: hBD-4 cDNA was cloned into pGEX-2T vector, and recombinant plasmid was transformed into E. ...
Optimization of physico-chemical properties of carbon enterosorbents and evaluation of their sorption activity for use in the treatment of paraneoplastic syndrome and other endogenous intoxications in cancer patients

Sarnatskaya, V.V.; Sidorenko, A.S.; Klymchuk, D.A.; Khohulya, I.M.; Yushko, L.A.; Maslenniy, V.N.; Nikolaev, V.G. (Experimental Oncology, 2013)

Aim - development of carbon enterosorbents with optimal physical-chemical properties and high adsorptive capacity for their usage in the treatment of paraneoplastic syndrome and other endogenous intoxication in cancer ...
Vitamin C: attenuating effect on growth and proliferation in systemic malignancies

Kapoor, S. (Experimental Oncology, 2013)

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Перегляд Experimental Oncology, 2013 (том 35) за датою випуску

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