Наукова електронна бібліотека
періодичних видань НАН України

Перегляд Experimental Oncology, 2012 (том 34) за датою випуску

Репозиторій DSpace/Manakin

Перегляд Experimental Oncology, 2012 (том 34) за датою випуску

Сортувати за: Порядок: Результатів:

  • Polymorphisms of MTHFR and MTR genes are not related to susceptibility to childhood ALL in north India 
    Nikbakht, M.; MalekZadeh, K.; Kumar Jha, A.; Askari, M.; Marwaha, R.K.; Kaul, D.; Kaur, J. (Experimental Oncology, 2012)
    Background:Acute lymphoblastic leukemia (ALL) is the most worldwide common type of childhood cancer. Methylenetetrahydrofolate reductase (MTHFR) and 5-methyltetrahydrofolate-homocysteine methyltransferase (MTR) participate ...
  • Novel germline MLH1 and MSH2 mutations in latvian Lynch syndrome families 
    Berzina, D.; Irmejs, A.; Kalniete, D.; Borosenko, V.; Nakazawa-Miklasevica, M.; Ribenieks, K.; Trofimovics, G.; Gardovskis, J.; Miklasevics, E. (Experimental Oncology, 2012)
    Background/Aims: Hereditary non-polyposis colorectal cancer or Lynch syndrome is an autosomal dominantly inherited disease with high penetrance, mostly due to mutations in the MLH1 and MSH2 genes. The aim of this study is ...
  • Influence of surgical resection no plasma Endoglin (CD105) level in non-small cell lung cancer patients 
    Kopczynska, E.; Dancewicz, M.; Kowalewski, J.; Makarewicz, R.; Kardymowicz, H.; Kaczmarczyk, A.; Tyrakowski, T. (Experimental Oncology, 2012)
    Background and Aim: Endoglin is a proliferation-associated antigen on endothelial cells and essential for angiogenesis. Soluble endoglin (s‑endoglin), formed by proteolytic cleavage of ectodomain of membrane receptor could ...
  • The multilevel regulation of CD95 signaling outcome 
    Yurchenko, M.; Shlapatska, L.M.; Sidorenko, S.P. (Experimental Oncology, 2012)
    CD95, also called Fas or APO-1, was the first death receptor (DR) identified and characterized. Studies on CD95 receptor signaling revealed the versatile principles of cell fate regulation via DR. DRs could exert both pro- ...
  • Caspase-8 regulation of TRAIL-mediated cell death 
    Crowder, R.N.; El-Deiry, W.S. (Experimental Oncology, 2012)
    Research on TNF-related apoptosis-inducing ligand (TRAIL) and TRAIL receptors has advanced tremendously over the past 17 years. Initial observations of TRAIL and TRAIL receptor-mediated tumor cell toxicity led to enthusiasm ...
  • Foreword to the special issue on apoptosis 
    Chekhun, V.F. (Experimental Oncology, 2012)
  • Nineteenth century research on cell death 
    Clarke, P.G.H.; Clarke, S. (Experimental Oncology, 2012)
    This paper reviews research on cell death in the 19th C. The first report of cell death was by Vogt in 1842, which was remarkably soon after the establishment of the cell theory by Schleiden and Schwann between 1838 and ...
  • Programmed cell death and apoptosis — where it came from and where it is going: From Elie Metchnikoff to the control of caspases 
    Maghsoudi, N.; Zaketi, Z.; Lockshin, R.A. (Experimental Oncology, 2012)
    The story of cell death began with the origins of cell biology, including important observations by Elie (Ilya) Metchnikoff, who realized that phagocytes engulfed dying cells. Most of the early studies were observational. ...
  • Clearing the final hurdles to mitochondrial apoptosis: regulation post cytochrome C release 
    Monian, P.; Jiang, X. (Experimental Oncology, 2012)
    In mammalian cells, the mitochondrial pathway of apoptosis plays a key role in various biological processes and has been extensively studied. One of the signature features of this pathway is permeabilization of the outer ...
  • c-FLIP, a master anti-apoptotic regulator 
    Safa, A.R. (Experimental Oncology, 2012)
    Cellular FLICE (FADD-like IL-1β-converting enzyme)-inhibitory protein (c-FLIP) is a master anti-apoptotic regulator and resistance factor that suppresses tumor necrosis factor-α (TNF-α), Fas-L, and TNF-related apoptosis-inducing ...
  • MicroRNAs and human cancer 
    Nikitina, E.G.; Urazova, L.N.; Stegny, V.N. (Experimental Oncology, 2012)
    MicroRNAs (miRNAs) are a recently discovered family of short non-coding RNA molecules of about 19–24 nucleotides in length that are involved in regulation of gene expression. These small molecules have been found to regulate ...
  • Inhibition of TGFβ signaling and its implications in anticancer treatments 
    Calone, I.; Souchelnytskyi, S. (Experimental Oncology, 2012)
    The transforming growth factor-β (TGFβ) is a potent regulator of tumorigenesis. In cancer, two distinctive behaviors of TGFβ have been reported as a tumor suppressor at early stage of the disease, and as a tumor promoter ...
  • Metformin plus PIAF combination chemotherapy for hepatocellular carcinoma 
    Petrushev, B.; Tomuleasa, C.; Soritau, O.; Aldea, M.; Pop, T.; Susman, S.; Kacso, G.; Berindan, I.; Irimie, A.; Cristea, V. (Experimental Oncology, 2012)
    Objectives: Metformin, the most used oral antidiabetic drug for the treatment of type 2 diabetus mellitus, has proved encouraging results when used in the treatment of various types of cancer such as triple-negative breast ...
  • Primary extranodal Non-Hodgkin`s lymphoma presenting as painful gingval swelling 
    Urun, Y.; Can, F.; Baris, E.; Akbulut, H.; Utkan, G.; Icli, F. (Experimental Oncology, 2012)
    Primary extra-nodal non-Hodgkin’s lymphomas (NHL) constitute 25–40% of NHL but less than 1% arises in oral cavity. Here in 53-year-old man with stage IE gingival diffuse large B cell lymphoma who was treated successfully ...
  • 17-AAG mediates targeting of HSP90 limits tert activity in peritoneal sarcoma related malignant ascites by downregulating cyclin D1 during cell cycle entry 
    Chaklader, M.; Das, P.; Pereira, J.A.; Law, A.; Chattopadhyay, S.; Chatterjee, R.; Mondal, A.; Law, S. (Experimental Oncology, 2012)
    Aim: Peritoneal or retro-peritoneal sarcomatosis related malignant ascites formation is a rare but serious consequence of the locoregional metastatic event. The present work aimed to study the effect of the Hsp90 inhibitor ...
  • Initial experience with using frameless image-guided radiosurgery for the treatment of brain metastases 
    Liepa, Z.; Auslands, K.; Apskalne, D.; Ozols, R. (Experimental Oncology, 2012)
    Aim : Recent technologic advances have led to the development of frameless radiosurgery. We report our initial results using frameless image-guided radiosurgery for the management of brain metastases. Methods: Over a 2-year ...
  • Abnormalities of apoptosis of the thyroid gland cells from extratumoral microfollicular tissue 
    Myshunina, T.M.; Kalinichenko, O.V.; Tronko, N.D. (Experimental Oncology, 2012)
    Aim: The aim of this study was to evaluate the frequency of existence of thyroid extratumoral normo- and microfollicular tissue in patients with thyroid carcinoma and peculiarities of apoptosis in mentioned tissue. Materials ...
  • Cancer with unknown primary: finding a needle in a hay stack 
    Giesel, F.L.; Mehndiratta, A.; Mafomane, M.P.; Zechmann, C.M.; Bergmann, F.; Schemmer, P.; Haberkorn, U.; Kratochwil, C. (Experimental Oncology, 2012)
    Detection and resection of small neuroendocrine tumours (NET) is like finding a needle in a hay stack. Use of specific tracers such as 68Ga-DOTATOC in a PET/CT study has been proven to have a high sensitivity and specificity ...
  • Effects of IL-6, IL-10 and TGF-β on the expression of survivin and apoptosisin nasopharyngeal carcinoma TW01 cells 
    Poh, Y.W.; Gan, S.Y.; Tan, E.L. (Experimental Oncology, 2012)
    The aim of this study is to investigate whether IL-6, IL-10 and TGF-β are able to confer resistance to apoptosis in nasopharyngeal carcinoma cells by upregulating the expression of survivin. Methods: The human nasopharyngeal ...
  • The long-range cytotoxic effect in tumor-bearing animals 
    Gerashchenko, B.I.; Ryabchenko, N.M.; Glavin, O.A.; Mikhailenko, V.M. (Experimental Oncology, 2012)
    Aim:The relationship between cancer and patient health is still of great interest for experimental and clinical oncology. The tumor can adversely affect surrounding and distant tissues as well. However, effects of the tumor ...

Пошук


Розширений пошук

Перегляд

Мій обліковий запис