Перегляд за автором "Iarovaia, O.V."

Сортувати за: Порядок: Результатів:

  • C-methods to study 3D organization of the eukaryotic genome 
    Gavrilov, A.A.; Razin, S.V.; Iarovaia, O.V. (Вiopolymers and Cell, 2012)
    В последнее время становится все более очевидным, что пространственная организация эукариотического генома играет важную роль в регуляции экспрессии генов. Трехмерную (3D) организацию генома можно исследовать с помощью ...
  • Dynamic nature of active chromatin hubs 
    Gavrilov, A.A.; Philonenko, E.S.; Iarovaia, O.V.; Razin, S.V. (Вiopolymers and Cell, 2011)
    Aim. In order to get more information about organization of active chromatin hubs and their role in the regulation of gene transcription we have studied the spatial organization of the a-globin gene domain in cultured chicken ...
  • Intranuclear localization of transcription factories and immunoglobulin heavy chain gene alleles during human B-cell maturation 
    Pichugin, A.V.; Iarovaia, O.V.; Sklyar, I.V.; Lacombe, G.; Razin, S.V.; Fest, T.; Lipinski, M.; Vassetzky, Y.S. (Вiopolymers and Cell, 2016)
    Immunoglobulin heavy chain (IGH) gene locus is expressed monoallelically in human B cells. Aim. To study the role of nuclear organization in regulation of the IGH expression during B-cell differentiation. Methods. ...
  • Translocations affecting human immunoglobulin heavy chain locus 
    Sklyar, I.V.; Iarovaia, O.V.; Lipinski, M.; Vassetzky, Y.S. (Вiopolymers and Cell, 2014)
    Translocations involving human immunoglobulin heavy chain (IGH) locus are implicated in different leukaemias and lymphomas, including multiple myeloma, mantle cell lymphoma, Burkitt’s lymphoma and diffuse large B cell ...
  • Treatment of lymphoid cells with the topoisomerase II poison etoposide leads to an increased juxtaposition of AML1 and ETO genes on the surface of nucleoli 
    Rubtsov, M.A.; Glukhov, S.I.; Allinne, J.; Pichugin, A.; Vassetzky, Y.S.; Razin, S.V.; Iarovaia, O.V. (Вiopolymers and Cell, 2011)
    AML1 and ETO genes are known partners in the t(8,21) translocation associated with the treatment-related leukaemias in the patients receiving chemotherapy with DNA-topoisomerase II (topo II) poisons. Aim. To determine ...