Galbiatti, A.L.S.; Caldas, H.C.; Padovani Junior, J.A.; Pavarino, E.C.; Goloni-Bertollo, E.M.
(Experimental Oncology, 2012)
Aim: Methotrexate (MTX) is an antifolate agent that acts inhibiting purine and pyrimidine synthesis. The objective of the study was to evaluate the viability of Hep-2 human laryngeal cancer cells to the treatment with MTX ...