Перегляд за темою "Reviews"

Сортувати за: Порядок: Результатів:

  • Interaction of actin with plasminogen/plasmin system: mechanisms and physiological role 
    Tykhomyrov, A.A. (Вiopolymers and Cell, 2012)
    In the present review, we have summarized and analyzed the literature data concerning cooperation between multifunctional proteins, the components of plasminogen/plasmin system and actin. The mechanisms underlying intermolecular ...
  • ITSN protein family: regulation of diversity, role in signalling and pathology 
    Tsyba, L.O.; Dergai, M.V.; Skrypkina, I.Ya.; Nikolaienko, O.V.; Dergai, O.V.; Kropyvko, S.V.; Novokhatska, O.V.; Morderer, D.Ye.; Gryaznova, T.A.; Gubar, O.S.; Rynditch, A.V. (Вiopolymers and Cell, 2013)
    Adaptor/scaffold proteins of the intersectin (ITSN) family are important components of endocytic and signalling complexes. They coordinate trafficking events with actin cytoskeleton rearrangements and modulate the activity ...
  • Kombucha microbiome as a probiotic: a view from the perspective of post-genomics and synthetic ecology 
    Kozyrovska, N.O.; Reva, O.M.; Goginyan, V.B.; de Vera, J.-P. (Вiopolymers and Cell, 2012)
    Probiotics are essential for establishing and maintaining optimal immune health. The probiotic therapy is known from alternative medicine for ages; however, the recent demonstration of the normal microflora to induce innate ...
  • Lamina–associated chromatin in the context of the mammalian genome folding 
    Ulianov, S.V.; Shevelyov, Y.Y.; Razin, S.V. (Вiopolymers and Cell, 2016)
    Eukaryotic interphase chromatin is folded hierarchically. Mammalian chromosomes are partitioned into topo-logically associating domains (TADs) whose interactions with each other drive the spatial segregation of the bulk ...
  • Leukemic blast cells and controversies in models of hematopoiesis 
    Gluzman, D.F.; Sklyarenko, L.M.; Zavelevich, M.P.; Koval, S.V.; Ivanivskaya, T.S. (Experimental Oncology, 2015)
    Classical and up-to-date models of hematopoietic lineage determination are briefly reviewed with the focus on myeloid-based models challenging the existence of the common progenitor for T cells, B cells and NK cells. The ...
  • Lipoxygenase regulation in vivo and in vitro by lipid compounds 
    Skaterna, T.D.; Kopich, V.M.; Kharitonenko, G.I.; Kharchenko, O.V. (Вiopolymers and Cell, 2015)
    Lipoxygenases (LOs) are known as one of the enzymes of lipid peroxidation. The majority of LOs are soluble enzymes and have affinity to membranes. The enzyme translocation from a cytosol to a membrane surface is one of the ...
  • Lipoxygenase regulation in vivo and in vitro by lipid compounds 
    Skaterna, T.D.; Kopich, V.M.; Kharitonenko, G.I.; Kharchenko, O.V. (Вiopolymers and Cell, 2015)
    Lipoxygenases (LOs) are known as one of the enzymes of lipid peroxidation. The majority of LOs are soluble enzymes and have affinity to membranes. The enzyme translocation from a cytosol to a membrane surface is one of the ...
  • Mechanisms of DNA repair in mitochondria 
    Singatulina, A.S.; Pestryakov, P.E. (Вiopolymers and Cell, 2016)
    The role of mitochondria in cellular metabolism and functioning can hardly be overestimated. Mitochondria carry out many functions, and their main function is the production of ATP, the energetic “currency” of the cell. ...
  • MGMT expression: insights into its regulation. 1. Epigenetic factors 
    Iatsyshyna, A.P. (Вiopolymers and Cell, 2013)
    O⁶-methylguanine-DNA methyltransferase (MGMT) is the DNA repair enzyme responsible for removing of alkylation adducts from the O6-guanine in DNA. Despite MGMT prevents mutations and cell death, this enzyme can provide ...
  • MGMT expression: insights into its regulation. 2. Single nucleotide polymorphisms 
    Iatsyshyna, A.P.; Pidpala, O.V.; Lukash, L.L. (Вiopolymers and Cell, 2013)
    High intra- and interindividual variations in the expression levels of the human O6-methylguanine-DNA methyltransferase (MGMT) gene have been observed. This DNA repair enzyme can be a cause of resistance of cancer cells ...
  • MicroRNAs and human cancer 
    Nikitina, E.G.; Urazova, L.N.; Stegny, V.N. (Experimental Oncology, 2012)
    MicroRNAs (miRNAs) are a recently discovered family of short non-coding RNA molecules of about 19–24 nucleotides in length that are involved in regulation of gene expression. These small molecules have been found to regulate ...
  • MicroRNAs in normal and cancer cells: a new class of gene expression regulators 
    Bagnyukova, T.V.; Pogribny, I.P.; Chekhun, V.F. (2006)
    MicroRNAs (miRNAs) are small non-coding RNAs that negatively regulate gene expression at posttranscriptional level. They are involved in cellular development, differentiation, proliferation and apoptosis and play a significant ...
  • Mitochondrial genetic transformation via biotechnological approaches or natural competence mechanism: do we have a choice? 
    Koulintchenko, M.V.; Dietrich A.; Konstantinov, Yu.M. (Вiopolymers and Cell, 2012)
    Несмотря на достаточно убедительные доказательства существования горизонтального переноса генов в растительные митохондрии, в этой области исследований остается много нерешенных вопросов, в частности, не известен молекулярный ...
  • Mobile genetic elements and cancer. From mutations to gene therapy 
    Kozeretska, I.A.; Demydov, S.V.; Ostapchenko, L.I. (Experimental Oncology, 2011)
    In the present review, an association between cancer and the activity of the non-LTR retroelements L1, Alu, and SVA, as well as endogenous retroviruses, in the human genome, is analyzed. Data suggesting that transposons ...
  • Model DNA for investigation of mechanism of nucleotide excision repair 
    Evdokimov, A.N.; Lavrik, O.I.; Petruseva, I.O. (Вiopolymers and Cell, 2014)
    The living cell DNA is under permanent attack of a variety of exogenous and endogenous damaging factors. Nucleotide excision repair (NER) is main pathway which removes a wide variety of bulky DNA adducts formed by UV light, ...
  • Modern views on the structure and dynamics of biological membranes 
    Demchenko, A.P. (Вiopolymers and Cell, 2012)
    Essential changes have been recently observed in views on the functioning, structural and dynamic properties of biological membranes. The previous results on hierarchical cluster-type structure of membranes and role of ...
  • Molecular and clinical conditions associated with venous thromboembolism in oncological patients 
    Micco, P. Di; Amitrano, M.; Niglio, A.; Fontanella, A. (Experimental Oncology, 2006)
    The association between cancer and thrombophilia has been known since 1865 since Trousseau described it. However in the last three decades an increased interest has been raised on this issue related to several molecular ...
  • Molecular and genetics approaches for investigation of phospholipase D role in plant cells 
    Kravets, V.S.; Kolesnikov, Ya.S.; Kretynin, S.V.; Kabachevskaya, E.M.; Liahnovitch, G.V.; Bondarenko, O.M.; Volotovsky, I.D.; Kukhar, V.P. (Вiopolymers and Cell, 2010)
    The review is devoted to the analysis of publications concerning the role of phospholipase D (PLD) in regulation of metabolism in plant cells. Analysis of molecular and genetic studies suggest that PLD is an important ...
  • Molecular genetic biotechnologies – the way to the welfare of the people and increasing of agriculture profitability 
    Potopalsky, A.I.; Bolsunova, O.I.; Zaika, L.A. (Вiopolymers and Cell, 2013)
    We have designed and offered a comprehensive approach to solving several problems in modern agriculture and human health. It is based on the original use of biotechnology. The mechanisms of alkylation of amines, nucleic ...
  • Molecular markers of apoptosis in cancer patients exposed to ionizing radiation: the post-chornobyl view 
    Philchenkov, A.A.; Balcer-Kubiczek, E.K. (Experimental Oncology, 2016)
    During the past three decades, the deleterious consequences of Chornobyl accident including carcinogenic effects in the people who were accidentally exposed to radiation have been intensively studied. In particular, recent ...