Перегляд за темою "Reviews"

Сортувати за: Порядок: Результатів:

  • Molecular mechanisms of versatile biological activity of interleukin-7 
    Slyvka, A.V.; Okunev, O.V. (Вiopolymers and Cell, 2014)
    As a result of immunological studies of the last 25 years it turned out that interleukin-7 (IL-7) is one of the most important regulatory cytokines of the immune system. It is special in many concerns. Having a strong ...
  • Molecular profiling and genomic microarrays in prostate cancer 
    Golias, Ch.; Charalabopoulos, A.; Stagikas, D.; Giannakopoulos, X.; Peschos, D.; Batistatou, A.; Sofikitis, N.; Charalabopoulos, K. (Experimental Oncology, 2007)
    In the present review article a global approach regarding the usefulness of genomic microarrays in prostate cancer management, is attempted. Cancer is a multistep process of mutations in key regulatory genes and epigenetic ...
  • Mutations in the gene of human type IIb sodium-phosphate cotransporter SLC34A2 
    Lituiev, D.S.; Kiyamova, R.G. (Вiopolymers and Cell, 2010)
    Type IIb sodium-phosphate cotransporter (NaPi2b) provides phosphate intake in the cells of some epithelial tissues, osteoblasts and odontoblasts. Abnormal expression of NaPi2b has been detected in some types of epithelial ...
  • Neutrophil-tumor cell phagocytosis (cannibalism) in human turoms: an update and literature review 
    Caruso, R.A.; Fedele, F.; Finocchiaro, G.; Arena, G.; Venuti, A. (Experimental Oncology, 2012)
    The recognition and removal of apoptotic cells by tissue macrophages and nonprofessional phagocytes, in a process called efferocytosis, is critical for development, tissue homeostasis and resolution of inflammation. Apoptotic ...
  • Nineteenth century research on cell death 
    Clarke, P.G.H.; Clarke, S. (Experimental Oncology, 2012)
    This paper reviews research on cell death in the 19th C. The first report of cell death was by Vogt in 1842, which was remarkably soon after the establishment of the cell theory by Schleiden and Schwann between 1838 and ...
  • Nitric oxide as the main multifunctional regulator of immunocompetent and endothelial cells 
    Sadlyak, O.V.; Kolishetska, M.A.; Baida, M.L.; Musij-Sementsiv, Kh.G.; Sementsiv, N.G.; Lesyk, R.B. (Вiopolymers and Cell, 2017)
    Nitric oxide (NO) plays an important role in metabolism. Consequently, every tissue of our body is affected by changes in concentrations of nitric oxide and its metabolites. Here we analyze phenotypic effects of NO and its ...
  • Nitrosative events in atopic asthma pathogenesis 
    Parilova, O.O.; Volodina, T.T.; Shandrenko, S.G. (Вiopolymers and Cell, 2015)
    The correlation between high exhaled nitric oxide levels and eosinophilic-mediated airway inflammation in patients with atopic asthma has been well documented. This generates prerequisites that a regulatory feedback mechanism ...
  • Nonchromosomal cytogenetic analysis of mammal somatic cells 
    Kovalova, O.A.; Bezdenezhnykh, N.A.; Kudryavets, Y.I. (Вiopolymers and Cell, 2013)
    The mutational events that take place in mammalian somatic cells influenced with different endogenous and exogenous factors are presented in this review. The nonchromosomal method of research allows taking into account the ...
  • Novel aspects of platelet aggregation 
    Roka-Moya, Y.M.; Bilous, V.L.; Zhernossekov, D.D.; Grinenko, T.V. (Вiopolymers and Cell, 2014)
    The platelet aggregation is an important process, which is critical for the hemostatic plug formation and thrombosis. Recent studies have shown that the platelet aggregation is more complex and dynamic than it was previously ...
  • Novel epigenetic markers of early epithelial tumor growth and prognosis 
    Gordiyuk, V.V.; Kondratov, A.G.; Gerashchenko, G.V.; Kashuba, V.I. (Вiopolymers and Cell, 2013)
    The present work is aimed at clarifying genetic and epigenetic alterations that occur during carcinogenesis and designing perspective sets of newly identified biomarkers. The tumors of kidney, cervix, colon, ovary, and ...
  • Nuclear receptors and their role in epstein — barr virus induced b cell transformation 
    Yenamandra, S.P.; Klein, G.; Kashuba, E. (Experimental Oncology, 2009)
    Epstein — Barr virus (EBV) is a lymphotropic virus that infects more than 90% of the human population, and targets B cells for infection. Infection of human B cells leads to the malignant transformation and eventual ...
  • Nucleosomal packaging of eukaryotic DNA and regulation of transcription 
    Golov, A.K.; Razin, S.V.; Gavrilov, A.A. (Вiopolymers and Cell, 2014)
    The eukaryotic nucleus harbors genomic DNA, which is tens of thousands of times greater in linear size than the nuclear diameter. Its high condensation is due to DNA packaging in chromatin, and DNA wrapping around nucleosomal ...
  • Nucleosome conformational flexibility in experiments with single chromatin fibers 
    Sivolob, A.V. (Вiopolymers and Cell, 2010)
    Studies on the chromatin nucleosome organization play an ever increasing role in our comprehension of mechanisms of the gene activity regulation. This minireview describes the results on the nucleosome conformational ...
  • Overview of methods of reverse engineering of gene regulatory networks: Boolean and Bayesian networks 
    Frolova, A.O. (Вiopolymers and Cell, 2012)
    Одна из проблем современной системной биологии – моделирование сетей генной регуляции, в наиболее полной мере отображающих регуляторные взаимодействия между генами всего организма. Большая вычислительная сложность такой ...
  • Overview on association of different types of leukemias with radiation exposure 
    Gluzman, D.F.; Sklyarenko, L.M.; Zavelevich, M.P.; Koval, S.V.; Ivanivska, T.S.; Rodionova, N.K. (Experimental Oncology, 2015)
    Exposure to ionizing radiation is associated with increasing risk of various types of hematological malignancies. The results of major studies on association of leukemias and radiation exposure of large populations in Japan ...
  • Paraneoplastic syndrome in lung cancer 
    Dumansky, Yu.V.; Syniachenko, O.V.; Stepko, P.A.; Yehudina, Ye.D.; Stoliarova, O.Yu. (Experimental Oncology, 2018)
    Aim: To study the nature of different variants of paraneoplastic syndrome (PNPS) in lung cancer, taking into account the features of the tumorous process and the complications of radiochemotherapy. Patients and Methods: ...
  • Paraneoplastic syndrome in lung cancer 
    Dumansky, Yu.V.; Syniachenko, O.V.; Stepko, P.A.; Yehudina, Ye.D.; Stoliarova, O.Yu. (Experimental Oncology, 2018)
    Aim: To study the nature of different variants of paraneoplastic syndrome (PNPS) in lung cancer, taking into account the features of the tumorous process and the complications of radiochemotherapy. Patients and Methods: ...
  • Photochemoprevention of cutaneous neoplasia through natural products 
    Filip, A.; Clichici, S.; Daicoviciu, D.; Adriana, M.; Postescu, I.D.; Perde-Schrepler, M.; Olteanu, D. (Experimental Oncology, 2009)
    Non-melanoma skin cancers such as squamous cell carcinoma and basal cell carcinoma are the most common types of human tumors, representing 30% of the new cases of malignancies diagnosed each year. Ultraviolet radiation ...
  • Photodynamic therapy in the treatment of glioma 
    Zavadskaya, Т.S. (Experimental Oncology, 2015)
    The review presents the data on the use of photodynamic therapy (PDT) for the treatment of patients with malignant brain tumors. One and two-year survival rate and an increase in overall median survival of PDT-treated ...
  • PI3K/mTOR/S6K signaling pathway – new players and new functional links 
    Filonenko, V.V. (Вiopolymers and Cell, 2013)
    This review summarizes experimental data related to the studies of PI3K/mTOR/S6K signaling conducted at the department of cell signaling. Analysis of novel S6Ks protein-protein interactions provided valuable information ...