Наукова електронна бібліотека
періодичних видань НАН України
періодичних видань НАН України
Markers of epithelial-mesenchymal transition in renal cell carcinoma
Репозиторій DSpace/Manakin
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| dc.contributor.author | Dumanskiy, Y.V. | |
| dc.contributor.author | Kudriashov, A.G. | |
| dc.contributor.author | Vasilenko, I.V. | |
| dc.contributor.author | Kondratyuk, R.B. | |
| dc.contributor.author | Gulkov, Y.K. | |
| dc.contributor.author | Chystiakov, R.S. | |
| dc.date.accessioned | 2019-01-20T09:05:57Z | |
| dc.date.available | 2019-01-20T09:05:57Z | |
| dc.date.issued | 2013 | |
| dc.identifier.citation | Markers of epithelial-mesenchymal transition in renal cell carcinoma / Y.V. Dumanskiy, A.G. Kudriashov, I.V. Vasilenko, R.B. Kondratyuk, Y.K. Gulkov, R.S. Сhystiakov // Experimental Oncology. — 2013. — Т. 35, № 4. — С. 325-327. — Бібліогр.: 14 назв. — англ. | uk_UA |
| dc.identifier.issn | 1812-9269 | |
| dc.identifier.uri | http://dspace.nbuv.gov.ua/handle/123456789/145287 | |
| dc.description.abstract | Aim - to study the influence of markers of epithelial-mesenchymal transition (EMT) on a renal cell carcinoma (RCC) prognosis. The surgical material of 47 RCC patients who underwent nephrectomy was studied. RCC patients were distributed in two groups: a short-term survival group (3 - 6 months) and a long-term survival group (17 - 24 months). EMT markers expression was assessed by immunohistochemical methods. It was determined that the rate of spindle-cell EMT was 96,4 % in a short-term survival group and 42,1 % in a long-term survival group. High rate Furhman's nuclear atypia, i.e. degree 3 - 4 occurred in 100 % of cases in a short-term survival group versus 68,4 % in a longterm survival group. Conclusion: the rate of spindle-cell EMT in RCC may serve a more sensible prognostic factor than the degree of Furhman's nuclear atypia. Key Words: renal cell carcinoma, epithelial-mesenchymal transition, the degree of Furhman’s nuclear atypia. | uk_UA |
| dc.language.iso | en | uk_UA |
| dc.publisher | Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України | uk_UA |
| dc.relation.ispartof | Experimental Oncology | |
| dc.subject | Arrticles not related to special issue topics | uk_UA |
| dc.title | Markers of epithelial-mesenchymal transition in renal cell carcinoma | uk_UA |
| dc.type | Article | uk_UA |
| dc.status | published earlier | uk_UA |
