Зависимость пародонтопротекторного действия липополисахарида (ЛПС) от индекса массы тела детей

Abstract

Оральные аппликации в течение 2-х недель геля с ЛПС детям 12 лет достоверно снижают уровень пародонтальных индексов (РМА, кровоточивости) через 1 и 6 месяцев и даже в некоторой степени через 12 месяцев. Пародонтопротекторное действие геля с ЛПС максимально проявляется у детей с ИМТ=20-25, а самое низ кое у детей с ИМТ<20.

Оральні аплікації на протязі 2 тижнів гелю з ЛПС дітям 12 років достовірно знижують рівень пародонтальних індексів (РМА, кровотечії) через 1 та 6 місяців і навіть в деякій мірі через 12 місяців. Пародонтопротекторна дія гелю з ЛПС максимально проявляється у дітей з ІМТ=20-25, а мінімально у дітей з ІМТ<20.

The aim: To determine periodontoprotective effect of oral applications of gel with LPS in children with different body weight indices (BWI). The materials and methods: LPS-containing preparation “Pyrogenal” in the contents of phytogel with the concentration of LPS 2 mcg/ml was used. 151 children at the age of 12 years were examined. The state of periodontium was estimated according to the level of periodontal indices: PMA, hemorrhage and Shiller-Pisarev’s one. The gel was applied on gums dosed at 0.5 ml every evening during 14 days. The state of periodontium was evaluated in 1, 6, 12 months. Gel with LPS was not used in the group of comparison. The children were divided into 3 groups depending on BWI: the 1st one – BWI = 20-25; the 2nd – BWI <20 and the 3rd – BWI >25. The findings: The oral applications of the gel with LPS caused the reduction of the level of periodontal indices, PMA and hemorrhage ones in greater degree. The periodontoprotective effect of gel with LPS, maximum expressed in a month, remained during a year and was the most obvious in the children with BWI = 20-25. Such effect of the gel with LPS was expressed in the least degree in children with BWI <20. The conclusion: The periodontoprotective effect of gel with LPS depends on BWI, being most obvious in children with normotrophy (BWI = 20-25).