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dc.contributor.author |
Zhang Ye |
|
dc.date.accessioned |
2018-06-16T17:23:41Z |
|
dc.date.available |
2018-06-16T17:23:41Z |
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dc.date.issued |
2017 |
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dc.identifier.citation |
Poly(lactic acid) scaffolds modified by gelatin for the controlled release of tetrandrine in vitro / Zhang Ye // Functional Materials. — 2017. — Т. 24, № 4. — С. 660-666. — Бібліогр.: 34 назв. — англ. |
uk_UA |
dc.identifier.issn |
1027-5495 |
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dc.identifier.other |
DOI: https://doi.org/10.15407/fm24.04.660 |
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dc.identifier.uri |
http://dspace.nbuv.gov.ua/handle/123456789/136891 |
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dc.description.abstract |
To mimic natural extracellular matrix architecture, tetrandrine-loaded poly(L-lactic acid) scaffolds modified by gelatin were prepared via phase separation, solvent replacement and freeze-drying. The purpose of this work was to combine the biological effects of tetrandrine and the advantages of poly(L-lactic acid) scaffolds which was modified by gelatin to enhancing the mass transfer features of controlled release systems. Tetrandrine contained in the scaffolds was confirmed by X-ray photoelectron spectroscopy (XPS) and Fourier-transform infrared (FT-IR) spectroscopy. Tetrandrine did not change the morphous, crystallinity and thermodynamics of the scaffolds which demonstrated by differential scanning calorimetry (DSC), scanning electron microscopy (SEM) and X-ray powder diffractometry (XRD). The results of this study showed a sustained release with 79.15% for 188 days in vitro. |
uk_UA |
dc.language.iso |
en |
uk_UA |
dc.publisher |
НТК «Інститут монокристалів» НАН України |
uk_UA |
dc.relation.ispartof |
Functional Materials |
|
dc.subject |
Technology |
uk_UA |
dc.title |
Poly(lactic acid) scaffolds modified by gelatin for the controlled release of tetrandrine in vitro |
uk_UA |
dc.type |
Article |
uk_UA |
dc.status |
published earlier |
uk_UA |
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