Перегляд за автором "Novokhatska, O.V."

Сортувати за: Порядок: Результатів:

  • Differential recognition of ITSN2/Ese2 by the SH2 domains of Fyn, Abl1, PLCg1 and PI3KR1 in mouse tissues 
    Novokhatska, O.V.; Pankivskyy, S.V.; Dergai, M.V.; Tsyba, L.O.; Rynditch, A.V. (Вiopolymers and Cell, 2013)
    Phosphorylation of endocytic adaptor ITSN2 that enabled its interaction with the SH2 domains of signaling proteins was recently reported. The aim of this study was to determine whether tissue-specific ITSN2 phosphorylation ...
  • Expression of ITSN2 and TKS5 in different subtypes of breast cancer tumors 
    Kropyvko, S.V.; Tsyba, L.O.; Novokhatska, O.V.; Nemesh, Y.M.; Syvak, L.A.; Tarasenko, T.Ye.; Grabovoy, A.N.; Rynditch, A.V. (Вiopolymers and Cell, 2019)
    Aim. Regardless a great progress in treatment, 15% of breast cancer cases remain lethal. One of the main problems in diagnosis and cure of this cancer type is its high clinical and genetic heterogeneity, and the identification ...
  • ITSN protein family: regulation of diversity, role in signalling and pathology 
    Tsyba, L.O.; Dergai, M.V.; Skrypkina, I.Ya.; Nikolaienko, O.V.; Dergai, O.V.; Kropyvko, S.V.; Novokhatska, O.V.; Morderer, D.Ye.; Gryaznova, T.A.; Gubar, O.S.; Rynditch, A.V. (Вiopolymers and Cell, 2013)
    Adaptor/scaffold proteins of the intersectin (ITSN) family are important components of endocytic and signalling complexes. They coordinate trafficking events with actin cytoskeleton rearrangements and modulate the activity ...
  • Novel isoform of adaptor protein ITSN1 forms homodimers via its C-terminus 
    Dergai, M.V.; Dergai, O.V.; Tsyba, L.O.; Novokhatska, O.V.; Skrypkina, I.Ya.; Rynditch, A.V. (Вiopolymers and Cell, 2011)
    Aim. Previously we have identified a novel isoform of endocytic adaptor protein ITSN1 designated as ITSN1- 22a. Western blot revealed two immunoreactive bands of 120 and 250 kDa that corresponded to ITSN1-22a. The goal ...
  • RTK signaling regulator SPRY2 associates with endocytic adaptor ITSN1 in vivo 
    Novokhatska, O.V.; Skrypkina, I.Ya.; Dergai, M.V.; Tsyba, L.O.; Rynditch, A.V. (Вiopolymers and Cell, 2012)
    Передача митогенного сигнала от RTK (рецепторных тирозиновых киназ) тесно связана с эндоцитозом, регулирующим ее точность. Интерсектин 1 (ITSN1) – эволюционно-консервативный адапторный белок, вовлеченный в самые ранние ...