Перегляд за автором "Sjakste, N."

Результати 1-7 з 7

Association between the PSMB5 and PSMC6 genetic variations and children obesity in the Latvian population

Paramonova, N.; Kupca, S.; Rumba-Rozenfelde, I.; Sjakste, N.; Sjakste, T. (Вiopolymers and Cell, 2014)

According to the recent data the ubiquitin-proteasome system (UPS) is implicated in the pathogenesis of obesity. Aim of our study was to evaluate a possible association between genetic variations in the PSMB5 and PSMC6 ...
DNA-binding studies of a series of novel water-soluble derivatives of 1,4-dihydropyridine

Leonova, E.; Rostoka, E.; Baumane, L.; Borisovs, V.; Smelovs, E.; Bisenieks, I.; Brūvere, I.; Bisenieks, E.; Duburs, G.; Sjakste, N. (Вiopolymers and Cell, 2018)

Aim. to determine DNA interaction modes for a series of 1,4-dihydropyridines with different biological activities synthesized in the Latvian Institute of Or-ganic Synthesis. Methods. Affinity of the compounds to DNA was ...
Experimental and human population studies of DNA lesions in healthy individuals

Sjakste, N. (Вiopolymers and Cell, 2017)

DNA damage is a valuable biomarker in human molecular epidemiology being associated with many diseases. However, the level of DNA damage is influenced also by intrinsic features of healthy individuals: heredity, sex, age ...
Genetic variants in the PSMA6, PSMC6 and PSMA3 genes associated with childhood asthma in Latvian and Taiwanese populations

Paramonova, N.; Wu, L.ShiShin; Rumba-Rozenfelde, I.; Wang, J.Y.; Sjakste, N.; Sjakste, T. (Вiopolymers and Cell, 2014)

Proteasomes mediate functional realization of signaling proteins implicated in asthma pathogenesis. Aim. To evaluate main and sex-specific association between the PSMA6, PSMC6 and PSMA3 proteasomal genes variations and ...
Structural and functional significance of microsatellites

Sjakste, T.; Paramonova, N.; Sjakste, N. (Вiopolymers and Cell, 2016)

Here we review literature data on impact of microsatellite repeats on DNA and chromatin structure and the results of studies on association between the length of microsatellite repeats and predisposition to pathologies. ...
Study of association between polymorphisms in the PSMB5 (rs11543947) and PSMA3 (rs2348071) genes and multiple sclerosis in Latvians

Kalnina, J.; Paramonova, N.; Sjakste, N.; Sjakste, T. (Вiopolymers and Cell, 2014)

Functional realization of many signalling proteins and transcription factors implicated in the development and progression of multiple sclerosis is mediated by proteasomes. Aim of this case-control study was to evaluate ...
Tightly-bound to DNA proteins in rat experimental hepatomas and normal liver cells

Labeikyte, D.; Borutinskaite, V.; Legzdins, N.; Sjakste, N. (Experimental Oncology, 2011)

Proteins tightly bound to DNA (TBP) comprise a group of proteins that remain bound to DNA even after harsh deproteinization procedures. The amount of these proteins is 20–100 µg for mg of DNA depending on eukaryotic source. ...

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Перегляд за автором "Sjakste, N."

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Перегляд за автором "Sjakste, N."

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