Перегляд за автором "Rath, M."

Результати 1-12 з 12

Antiangiogenic properties of a nutrient mixture in a model of hemangioma

Roomi, M.W.; Kalinovsky, T.; Niedzwiecki, A.; Rath, M. (Experimental Oncology, 2009)

The pathogenesis of hemangiomas is still largely unknown and the current therapy, such as systemic corticosteroid, vincristine, and interferon-alpha, is toxic and remains unsatisfactory. A nutrient mixture (NM) containing ...
Antineoplastic effects of nutrient mixture on Raji and Jurkat t cells: the two highly aggressive non hodgkin’s lymphoma cell lines

Roomi, M.W.; Bhanap, B.A.; Roomi, N.W.; Rath, M.; Niedzwiecki, A. (Experimental Oncology, 2009)

Non-Hodgkin lymphomas incidence has increased more than 70% in last 25 years. Aggressiveness, higher relapse rate, and treatment complications pose significant barriers. Decreased food intake and side effects of treatments ...
A nutrient mixture inhibits glioblastoma xenograft U-87 MG growth in male nude mice

Roomi, M.W.; Kalinovsky, T.; Rath, M.; Niedzwiecki, A. (Experimental Oncology, 2016)

Background: Brain tumors are highly aggressive tumors characterized by secretions of high levels of matrix metalloproteinase-2 and -9, leading to tumor growth, invasion and metastasis by digesting the basement membrane and ...
Ascorbate depletion increases growth and metastasis of melanoma cells in vitamin C deficient mice

Cha, J.; Roomi, M.W.; Ivanov, V.; Kalinovsky, T.; Niedzwiecki, A.; Rath, M. (Experimental Oncology, 2011)

Aim: Our main objective was to determine the effect of ascorbate supplementation in mice unable to synthesize ascorbic acid (gulo KO) when challenged with murine B16FO cancer cells. Methods: Gulo KO female mice 36–40 weeks ...
Down regulation of u-PA by a nutrient mixture in hemangioma (EOMA) cells by inducing caspase-dependent apoptosis

Roomi, M.W.; Bhanap, B.; Niedzwiecki, A.; Rath, M. (Experimental Oncology, 2018)

Hemangiomas are the most common congenital vascular and benign tumor in infants and children. Most hemangiomas do not cause major symptoms to require intervention, however, the larger hemangiomas have tendency to bleed and ...
Inhibition of growth and expression of inflammation mediators in human leukemic cell line U-937 by a nutrient mixture

Roomi, M.W.; Kalinovsky, T.; Roomi, N.W.; Rath, M.; Niedzwiecki, A. (Experimental Oncology, 2013)

Aim: A nutrient mixture (NM) containing ascorbic acid, lysine, proline and green tea extract has exhibited anticancer activity in vitro and in vivo in a number of cancer cell lines. We investigated the effect of NM on human ...
Inhibition of invasion and MMPs by a nutrient mixture in human cancer cell lines: a correlation study

Roomi, M.W.; Monterrey, J.C.; Kalinovsky, T.; Rath, M.; Niedzwiecki, A. (Experimental Oncology, 2010)

The aim of this paper is to examine the correlation between in vitro MMP-2 and MMP-9 secretion and Matrigel invasion in 42 different human cancer cell lines (selected on the basis of organ malignancies) treated with a ...
In vitro inhibition of matrix metalloproteinases, invasion and growth of Fanconi anemia human FANCA and FANCC lymphoblasts by nutrient mixture

Roomi, M.W.; Bhanap, B.; Roomi, N.W.; Niedzwiecki, A.; Rath, M. (Experimental Oncology, 2014)

Aim: Fanconi anemia is a rare genetic disorder with high propensity for development of cancers, such as aplastic anemia, leukemia and head and neck cancers. Collagen digesting matrix metalloproteinase (MMP) enzymes have ...
In vivo and in vitro antitumor effects of nutrient mixture in murine leukemia cell line P-388

Roomi, M.W.; Roomi, N.W.; Bhanap, B.; Rath, M.; Niedzwiecki, A. (Experimental Oncology, 2011)

Aim: Leukemia is characterized by uncontrolled marrow cell proliferation and metastatic foci. We investigated the antitumor potential of a nutrient mixture on malignant leukemia P-388 cells. Methods: The nutrient mixture ...
In vivo and In vitro effect of a nutrient mixture on human hepatocarcinoma cell line SK-HEP-1

Roomi, M.W.; Roomi, N.W.; Kalinovsky, T.; Niedzwiecki, A.; Rath, M. (Experimental Oncology, 2010)

Long-term survival of patients with hepatocellular carcinoma (HCC), a common cancer worldwide, remains poor, due to metastasis and recurrence. Aim: To investigate the effect of a novel nutrient mixture (NM) containing ...
Nutrient mixture inhibits in vitro and in vivo growth of human acute promyelocytic leukemia HL-60 cells

Roomi, M.W.; Roomi, N.W.; Bhanap, B.; Rath, M.; Niedzwiecki, A. (Experimental Oncology, 2011)

Aim: Untreated acute promyelocytic leukemia is the most malignant form of acute leukemias, with median survival of less than one month. We investigated in vitro and in vivo synergistic effects of a nutrient mixture (NM) ...
Repression of matrix metalloproteinases and inhibition of cell invasion by a nutrient mixture, containing ascorbic acid, lysine, proline, and green tea extract on human fanconi anemia fibroblast cell lines

Roomi, M.W.; Roomi, N.W.; Bhanap, B.; Niedzwiecki, A.; Rath, M. (Experimental Oncology, 2013)

Aim: Fanconi Anemia, an autosomal recessive disorder, is characterized by chromosomal abnormality leading to birth defects, progressive bone marrow failure, and a high probability of developing malignancy at an early age. ...

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Перегляд за автором "Rath, M."

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