Перегляд за автором "Palchevskyy, S.S."

Сортувати за: Порядок: Результатів:

  • Dephosphorylation of tuberous sclerosis complex 2 by serine/threonine protein phosphatase 5 
    Malanchuk, O.M.; Palchevskyy, S.S.; Filonenko, V.V. (Біополімери і клітина, 2008)
    We report here for the first time specific interaction between tuberous sclerosis complex 2 (TSC2) and protein phosphatase 5 (PP5) in mammalian cells. We found that the interaction is stronger in exponentially growing and ...
  • Generation of monoclonal antibodies specific to ribosomal protein S6 kinase 1 
    Savinska, L.O.; Klipa, O.M.; Demchuk, N.O.; Ovcharenko, G.V.; Malanchuk, O.M.; Tykhonkova, I.O.; Palchevskyy, S.S.; Filonenko, V.V. (Вiopolymers and Cell, 2012)
    The aim of this study was to produce monoclonal antibodies directed to the N-terminal regulatory region of S6K1, which shows very low homology to S6K2. Methods. Hybridoma technology, ELISA, Western blot, Immunoprecipitation. ...
  • Generation of monoclonal antibody against protein phosphatase 5 
    Malanchuk, O.M.; Ovcharenko, G.V.; Tykhonkova, I.O.; Khoma, O.S.; Chorna, U.V.; Rybak, M.Yu.; Palchevskyy, S.S. (Вiopolymers and Cell, 2013)
    Aim. Serine/threonine protein phosphatase 5 (PP5) is a unique member of serine/threonine phosphatase family, comprises a regulatory tetratricopeptide repeat (TPR) domain and regulates many cell signaling pathways. Here, ...
  • Interaction of serine/threonine protein phosphatase 5 with the protein products of tumour suppressor gene Tsc2 
    Malanchuk, O.M.; Palchevskyy, S.S.; Pozur, V.K.; Gout, I.T.; Filonenko, V.V. (Біополімери і клітина, 2007)
    Tuberous sclerosis (TSC) is a tumour disease caused by mutations in Tsc1 or Tsc2 genes. Both protein products of Tsc1 and Tsc2 form an intracellular complex possessing GTPase-activating (GAP) activity towards a small GTP ...