Перегляд за автором "Nikolaev, V.G."

Результати 1-10 з 10

Carbon adsorbents in oncology: achievements and perspectives

Nikolaev, V.G.; Sakhno, L.A.; Snezhkova, E.A.; Sarnatskaya, V.V.; Yushko, L.A. (Experimental Oncology, 2011)

The results of own investigations and literature data are summarized to determine the place of the main methods of adsorption therapy in complex treatment of the patients with malignant tumors. New possibilities for the ...
Effect of enterosorption on paraneoplastic syndrome manifestations in mice with highly angiogenic variant of lewis lung carcinoma

Sarnatskaya, V.V.; Nikolaev, V.G.; Yushko, L.A.; Paziuk, L.M.; Karaman, O.M.; Fedosova, N.I.; Kolesnik, D.L.; Dasyukevich, O.I.; Gorbik, G.V.; Maslenny, V.N.; Solyanik, G.I. (Experimental Oncology, 2015)

Aim: To study the correcting effects of microgranulated HSGD enterosorbent on hematological, morphological and biochemical indices of paraneoplastic syndrome in mice with highly angiogenic variant of Lewis lung carcinoma ...
Enterosorption as a method to decrease the systemic toxicity of cisplatin

Sakhno, L.A.; Yurchenko, O.V.; Maslenniy, V.N.; Bardakhivskaya, K.I.; Nikolaeva, V.V.; Ivanyuk, A.A.; Shevchuk, O.O.; Korotich, V.G.; Nikolaev, V.G. (Experimental Oncology, 2013)

A perspective adsorptive method to minimize systemic toxic effects of chemotherapy is enterosorption (ES). However, the capabilities of this method are far from being completely studied. The question remains opened — should ...
Enterosorption combined with granulocyte colony stimulating factor decreases melphalan gonadal toxicity

Shevchuk, O.O.; Bodnar, Ya.Ya.; Bardakhivska, K.I.; Datsko, T.V.; Volska, A.S.; Posokhova, K.A.; Chekhun, V.F.; Nikolaev, V.G. (Experimental Oncology, 2016)

Today due to improvements in cancer treatment there is an increasing number of long-term cancer survivors, many of whom suffer from infertility caused by malignancy itself and chemo- or radiotherapy. Also, anticancer therapy ...
Highly activated carbon enterosorbent mediates the suppression of paraneoplastic syndrome associated with lewis lung carcinoma in mice

Sarnatskaya, V.V.; Sakhno, L.A.; Paziuk, L.M.; Yushko, L.A.; Rodionova, N.K.; Maslenny, V.N.; Sydorenko, A.S.; Nikolaev, V.G. (Experimental Oncology, 2018)

Aim: To investigate the effect of enterosorption on the development of paraneoplastic syndrome in mice with Lewis lung carcinoma (LLC). Materials and Methods: The study was performed on male С57/ВL6 mice with transplanted ...
Optimization of physico-chemical properties of carbon enterosorbents and evaluation of their sorption activity for use in the treatment of paraneoplastic syndrome and other endogenous intoxications in cancer patients

Sarnatskaya, V.V.; Sidorenko, A.S.; Klymchuk, D.A.; Khohulya, I.M.; Yushko, L.A.; Maslenniy, V.N.; Nikolaev, V.G. (Experimental Oncology, 2013)

Aim - development of carbon enterosorbents with optimal physical-chemical properties and high adsorptive capacity for their usage in the treatment of paraneoplastic syndrome and other endogenous intoxication in cancer ...
Prevention of myelosuppression by combined treatment with enterosorbent and granulocyte colony-stimulating factor

Shevchuk, O.O.; Posokhova, K.A.; Todor, I.N.; Lukianova, N.Yu.; Nikolaev, V.G.; Chekhun, V.F. (Experimental Oncology, 2015)

Hematotoxicity and its complication are the prominent limiting factors for rational treatment of malignancies. Granulocyte colony-stimulating factor (G-CSF) is used to increase granulocyte production. It has been shown ...
The influence of enterosorption on some haematological and biochemical indices of the normal rats after single injection of melphalan

Shevchuk, O.O.; Posokhova, К.А.; Sidorenko, A.S.; Bardakhivska, К.І.; Maslenny, V.M.; Yushko, L.A.; Chekhun, V.F.; Nikolaev, V.G. (Experimental Oncology, 2014)

Aim: One of the most prominent side effects of intensive cancer chemotherapy is bone marrow suppression which is an independent negative prognostic factor for the time to tumor progression. The aim of the study was to ...
Theoretical ground for adsorptive therapy of anthracyclines cardiotoxicity

Shevchuk, O.O.; Posokhova, E.A.; Sakhno, L.A.; Nikolaev, V.G. (Experimental Oncology, 2012)

Anthracyclines play an important role in treatment of variety types of cancer due to their high effectiveness and broad spectrum of activity. However, a major limitation of their use is the dose-limiting cardiotoxicity. ...
The study of possibility to elevate antitumor activity and decrease of systemic toxic effects of cisplatin by its binding with deliganded albumin

Sakhno, L.A.; Sarnatskaya, V.V.; Yushko, L.A.; Melnikov, O.R.; Momot, V.Ya.; Korneeva, L.N.; Svintsiskiy, V.S.; Korotich, V.G.; Nechitaylo, I.I.; Nikolaev, V.G. (2006)

Aim: To evaluate antitumor and toxic action of cisplatin (CP) in non-bound form and in a complex with deliganded albumin. Methods: To study complex-formation between CP and albumin, differential scanning and isothermic ...

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Перегляд за автором "Nikolaev, V.G."

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