Перегляд за автором "Melnikov, O.R."

Результати 1-4 з 4

Biodistribution analysis of cisplatin in liposomal form in animals with cisplatinresistant and cisplatin-sensitive carcinoma

Nosko, M.M.; Pivnyuk, V.M.; Solyanik, G.I.; Kulik, G.I.; Todor, I.N.; Momot, V.Ya.; Melnikov, O.R.; Ponomareva, O.V.; Chekhun, V.F. (Experimental Oncology, 2010)

Aim: To analyze the relation between pharmacokinetics of cisplatin in liposomal form and antitumor efficacy toward cisplatinresistant and cisplatin-sensitive variants of Guerin carcinoma. Concentration of platinum was ...
Dynamics of changes of antioxidant system indexes during the growth of two Lewis lung carcinoma variants

Pyaskovskaya, O.N.; Sorokina, L.V.; Kolesnik, D.L.; Boichuk, I.V.; Melnikov, O.R.; Solyanik, G.I. (Experimental Oncology, 2014)

Aim: To study an intensity of prooxidant processes and activity of antioxidant enzymes in tumor tissue of two Lewis lung carcinoma variants (LLC and LLC/R9) differing by their proliferative, metastatic, and angiogenic ...
Effect of dichloroacetate on Lewis lung carcinoma growth and metastasis

Kolesnik, D.L.; Pyaskovskaya, O.N.; Boychuk, I.V.; Dasyukevich, O.I.; Melnikov, O.R.; Tarasov, A.S.; Solyanik, G.I. (Experimental Oncology, 2015)

A hallmark of malignancy is excessive tumor glycolysis, even in the presence of oxygen, which causes lactacidosis in the tumor microenvironment and favors tumor cell proliferation and survival. For this reason antimetabolic ...
The study of possibility to elevate antitumor activity and decrease of systemic toxic effects of cisplatin by its binding with deliganded albumin

Sakhno, L.A.; Sarnatskaya, V.V.; Yushko, L.A.; Melnikov, O.R.; Momot, V.Ya.; Korneeva, L.N.; Svintsiskiy, V.S.; Korotich, V.G.; Nechitaylo, I.I.; Nikolaev, V.G. (2006)

Aim: To evaluate antitumor and toxic action of cisplatin (CP) in non-bound form and in a complex with deliganded albumin. Methods: To study complex-formation between CP and albumin, differential scanning and isothermic ...

Результати 1-4 з 4

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Перегляд за автором "Melnikov, O.R."

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Перегляд за автором "Melnikov, O.R."

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