Перегляд за автором "Denisov, E.V."

Сортувати за: Порядок: Результатів:

  • Age-related function of tumor suppressor gene TP53:contribution to cancer risk and progression 
    Cherdyntseva, N.V.; Gervas, P.A.; Litvyakov, N.V.; Stakcheeva, M.N.; Ponomaryeva, A.A.; Dobrodeev, A.Yu.; Denisov, E.V.; Belyavskaya, V.A.; Choinzonov, E.L. (Experimental Oncology, 2010)
    Aim: To examine the influence of combined genotypes of TP53 (exon 4, intron 3, intron 6) and XRCC1 (codon 10) on lung cancer age of onset. Methods: TP53 polymorphisms in codon 72 of exon 4 (Arg72Pro), in intron 3 (16 bp ...
  • Circulating tumor cells in breast cancer: functional heterogeneity, pathogenetic and clinical aspects 
    Cherdyntseva, N.V.; Litviakov, N.V.; Denisov, E.V.; Gervas, P.A.; Cherdyntsev, E.S. (Experimental Oncology, 2017)
    Each patient has a unique history of cancer ecosystem development, resulting in intratumor heterogeneity. In order to effectively kill the tumor cells by chemotherapy, dynamic monitoring of driver molecular alterations is ...
  • Different morphological structures of breast tumors demonstrate individual drug resistance gene expression profiles 
    Gerashchenko, T.S.; Denisov, E.V.; Novikov, N.M.; Tashireva, L.A.; Kaigorodova, E.V.; Savelieva, O.E.; Zavyalova, M.V.; Cherdyntseva, N.V.; Perelmuter, V.M. (Experimental Oncology, 2018)
    Aim: To identify gene expression profiles involved in drug resistance of different morphological structures (tubular, alveolar, solid, trabecular, and discrete) presented in breast cancer. Material and Methods: Ten patients ...
  • Different morphological structures of breast tumors demonstrate individual drug resistance gene expression profiles 
    Gerashchenko, T.S.; Denisov, E.V.; Novikov, N.M.; Tashireva, L.A.; Kaigorodova, E.V.; Savelieva, O.E.; Zavyalova, M.V.; Cherdyntseva, N.V.; Perelmuter, V.M. (Experimental Oncology, 2018)
    Aim: To identify gene expression profiles involved in drug resistance of different morphological structures (tubular, alveolar, solid, trabecular, and discrete) presented in breast cancer. Material and Methods: Ten patients ...
  • Heterogeneity of premetastatic niches gene expression in breast cancer cells 
    Tashireva, L.A.; Denisov, E.V.; Savelieva, O.E.; Geraschenko, T.S.; Zavyalova, M.V.; Perelmuter, V.M. (Вiopolymers and Cell, 2015)
    Aim. To investigate the expression of the genes TGFB1, TNF, CSF1, CSF2, VEGFA and HIF1A in the patients with invasive breast carcinoma of no special type considering the intratumoral morphological heterogeneity. Methods. ...
  • The phenomenon of multi-drug resistance in the treatment of malignant tumors 
    Vtorushin, S.V.; Khristenko, K.Y.; Zavyalova, M.V.; Perelmuter, V.M.; Litviakov, N.V.; Denisov, E.V.; Dulesova, A.Y.; Cherdyntseva, N.V. (Experimental Oncology, 2014)
    Multi-drug resistance (MDR) is a condition when there is broad cross-resistance of cells to various agents which are different in structure and effect. Modern perceptions on mechanisms of MDR development in malignant tumors ...