Влияние гербицида 2,4-дихлорфеноксиуксусной кислоты, сукцината натрия и их совместного применения на Mg^²+, Ca^²+ -АТФазную активность плазматической мембраны гепатоцитов

Abstract

One of the biochemical mechanisms of action of herbicide 2,4-dichlorophenoxyacetic acid (2,4-D) is its influence on the Mg^²+, Ca^²+-ATPase activity of hepatocytes plasma membrane after the subchronic introducing into rats (1/40 LD50) and in vitro (10^-9–10^-4 mol/l). Sodium succinate is less active in relation to this enzyme, however it is capable to oppress 2,4-D effects. It can be considered as protective properties of sodium succinate.