Перегляд Experimental Oncology за назвою

Сортувати за: Порядок: Результатів:

  • The TGF-beta — SMAD pathway is inactivated in cronic lymphocytic leukemia cells 
    Matveeva, A.; Kovalevska, L.; Kholodnyuk, I.; Ivanivskaya, T.; Kashuba, E. (Experimental Oncology, 2017)
    Aim: To study the status of the tumor growth factor beta (TGFB) pathway in chronic lymphocytic leukemia (CLL) cells and to uncover molecular details underlying CLL cell genesis. Objects and Methods: The study was conducted ...
  • The use of cardiac biomarkers in detection of cardiotoxicity associated with conventional and high-dose chemotherapy for acute leukemia 
    Horacek, J.M.; Vasatova, M.; Tichy, M.; Pudil, R.; Jebavy, L.; Maly, J. (Experimental Oncology, 2010)
    Aim: Monitoring of cardiotoxicity of conventional and high-dose chemotherapy (HD-CT) with multiple biomarkers of cardiac injury — glycogen phosphorylase BB (GPBB), heart-type fatty acid binding protein (H-FABP), cardiac ...
  • The use of doxorubicine at low doses for elevation of LAK-activity toward explants and cells of MC-rhabdomyosarcoma and В16 melanoma resistant to doxorubicin 
    Berezhnaya, N.M.; Vinnichuk, Yu.D.; Belova, O.B. (Experimental Oncology, 2008)
    Aim: To study the influence of doxorubicin at low doses on antitumor action of activated (LAK) and non-activated lymphocytes from lymph nodes toward tumor cells of mice bearing doxorubicin-resistant and doxorubicin-sensitive ...
  • The use of nanoferromagnetics to increase the cytotoxic effect of antitumor drugs 
    Chekhun, V.F.; Todor, I.N.; Lukyanova, N.Yu.; Shpyleva, S.I.; Naleskina, L.A.; Khaetsky, I.K.; Kulik, G.I. (Experimental Oncology, 2009)
    Aim: To investigate the influence of ferromagnetic nanoparticles on antitumor effect of doxorubicin and mitochondria oxidative phosphorylation. Methods: The study was carried out on the mice-hybrids (C57Bl/6xDBA/2) with ...
  • The use of proteomic technologies in breast cancer research 
    Mazur, M.G.; Pyatchanina, T.V. (Experimental Oncology, 2016)
    The main findings in the field of breast cancer proteomic research as well as modern strategies, technologies and methods of validation are reviewed. A special attention is focused on validated proteomic biomarkers of ...
  • Thromboelastographic profiles as a tool for thrombotic risk in digestive tract cancer 
    Papa, M.L.; Capasso, F.; Pudore, L.; Torre, S.; Mango, S.; Russo, V.; Delrio, P.; Palaia, R.; Ruffolo, F.; d’Eufemia, M.D.; De Lucia, D.; Napolitano, M.; Di Micco, P.; Parisi, V. (Experimental Oncology, 2007)
    Background: Quantification of the magnitude of thrombotic risk associated with malignancy and with anti-cancer therapy is indispensable to use anticoagulant drugs which selectively interfere with haemostatic mechanisms ...
  • Thrombotic complications during cancer treatment in children 
    Lipay, N.V.; Dmitriev, V.V.; Borisenok, M.B. (Experimental Oncology, 2007)
    Aim: To determine the hereditary risk factors contributing to the development of thrombosis in children with cancer. Methods: Sensitive PCR- restriction fragment length polymorphism assay. Results: There has been shown ...
  • Thyroid metastases from a breast cancer diagnosed by fine-needle aspiration biopsy. Case report and overview of the literature 
    Lacka, K.; Breborowicz, D.; Uliasz, A.; Teresiak, M. (Experimental Oncology, 2012)
    Aim: Intrathyroid metastases are uncommon in cytology practice. We report a case of metastatic lesion in the thyroid from breast carcinoma which was recognized in a fine-needle aspiration (FNA) biopsy and confirmed by ...
  • Tightly-bound to DNA proteins in rat experimental hepatomas and normal liver cells 
    Labeikyte, D.; Borutinskaite, V.; Legzdins, N.; Sjakste, N. (Experimental Oncology, 2011)
    Proteins tightly bound to DNA (TBP) comprise a group of proteins that remain bound to DNA even after harsh deproteinization procedures. The amount of these proteins is 20–100 µg for mg of DNA depending on eukaryotic source. ...
  • Tissue-engineered bone for treatment of combat related limb injuries 
    Vasyliev, R.G.; Oksymets, V.M.; Rodnichenko, A.E.; Zlatska, A.V.; Gubar, O.S.; Gordiienko, I.M.; Zubov, D.O. (Experimental Oncology, 2017)
    Aim: Based on our preliminary positive clinical results with use of cultured bone marrow-derived multipotent mesenchymal stem/stromal cells in traumatology, our aim was to develop living three-dimensional tissue-engineered ...
  • Tissue eosinophilia in head and neck squamous neoplasia: an update 
    Jain, M.; Kasetty, S.; Khan, S.; Jain, N. (Experimental Oncology, 2014)
    Eosinophils are multifunctional granulocytes that play an imperative role in health and disease. They have also been found to be a crucial component of peri- and intratumoral inflammatory infiltrate. Tumor-associated tissue ...
  • TNFα receptor1 drives hypoxia-promoted invasiveness of human melanoma cells 
    Marconi C.; Peppicelli S.; Bianchini F.; Calorini L. (Experimental Oncology, 2013)
    Aim: Oxygen deprivation leading to hypoxia represents a common feature of advanced solid tumors, able to control several aspects of tumor progression. Indeed, ability to respond to changes in oxygen partial pressure ...
  • TP53 codon 72 single nucleotide polymorphism in chronic lymphocytic leukemia 
    Bilous, N.I.; Abramenko, I.V.; Chumak, A.A.; Dyagil, I.S.; Martina, Z.V. (Experimental Oncology, 2014)
    Defects in the tumor suppressor gene TP53 are known to be important in chronic lymphocytic leukemia (CLL) and TP53 inactivation is associated with a particularly aggressive form of the disease. The single nucleotide ...
  • Translation control in apoptosis 
    Liwak, U.; Faye, M.D.; Holcik, M. (Experimental Oncology, 2012)
    Regulation of protein synthesis, although known for many decades, has only recently begun to be recognized as a critical control mechanism for the maintenance of cellular homeostasis and cellular stress response. One of ...
  • Treatment of large osteosarcoma in children: new approach 
    Kobys, V.L.; Konovalenko, V.F.; Repinа, N.V.; Golovko, T.S.; Gulak, L.O.; Tarasova, T.O.; Zaharycheva, E.V.; Matyushok, O.F. (Experimental Oncology, 2013)
    Aim - to improve the treatment results of patients with locally advanced osteosarcoma with large volume using neoadjuvant chemotherapy (NACT) (ifosfamide at a dose of 18 g/ml) and planning of organ-conserving surgery by ...
  • Treatment of metastatic head and neck cancer with mesenchymal stem cells combined with prodrug gene therapy 
    Lakota, J.; Gocarova, K.; Spanik, S. (Experimental Oncology, 2015)
    This is a clinical observation of a patient treated for metastatic head and neck cancer with mesenchymal stem cells mediated prodrug gene therapy. The cells were applied intravenously. We did not observe any therapeutic ...
  • Trichilemmal cystis in metastatic melanoma: a case report 
    Savarese, I.; Grazzini, M.; Gori, A.; D’Errico, A.; Doni, L.; Scarfì, F.; Covarelli, P.; Di Costanzo, F.; De Giorgi, V. (Experimental Oncology, 2017)
    The malignant melanoma is a neoplasm associated with a wide variety of cutaneous paraneoplastic syndromes, as dermatomyositis, systemic sclerosis, paraneoplastic pemphigus. We describe a case of four multiple trichilemmal ...
  • TRP genes family expression in colorectal cancer 
    Sozucan, Y.; Kalender, M.E.; Sari, I.; Suner, A.; Oztuzcu, S.; Arman, K.; Yumrutas, O.; Bozgeyik, I.; Cengiz, B.; Balakan, O.; Camci, C.; Igci, Y.Z. (Experimental Oncology, 2015)
    Colorectal cancer (CRC) is the most common cancer of the gastrointestinal tract. Different factors are responsible for the development of CRC. Transient Receptor Potential (TRP) which is an important component of calcium ...
  • "Tumor and host" by R.E. Kavetsky (1962): implications for the past, present and future 
    Osinsky, S.P.; Kelleher, D.K.; Chekhun, V.F. (Experimental Oncology, 2012)
  • Tumor cell heterogeneity 
    Chekhun, V.F.; Sherban, S.D.; Savtsova, Z.D. (Experimental Oncology, 2013)
    The paper deals with the analysis of literary data on the tumor cell heterogeneity. Phenotypic, genetic and epigenetic mechanisms of heterogeneity are considered. The heterogeneity or metastasis is considered too. The ...

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