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Перегляд Biopolymers and Cell за автором "Bdzhola, V.G."

Репозиторій DSpace/Manakin

Перегляд Biopolymers and Cell за автором "Bdzhola, V.G."

Сортувати за: Порядок: Результатів:

  • Evaluation of 4H-4-chromenone derivatives as inhibitors of protein kinase CK2 
    Prykhodko, A.O.; Yakovenko, O.Ya.; Golub, A.G.; Bdzhola, V.G.; Yarmoluk, S.M. (Біополімери і клітина, 2005)
    Protein kinase CK2 (Casein Kinase 2) is a ubiquitous serine/threonine protein kinase involved in various cell signal transduction pathways. Thus, CK2 is a new perspective target for anticancer drugs. The receptor-based ...
  • Hit identification of CK2 inhibitors by virtual screening 
    Protopopov, M.V.; Starosyla, S.A.; Borovykov, O.V.; Sapelkin, V.N.; Bilokin, Y.V.; Bdzhola, V.G.; Yarmoluk, S.M. (Вiopolymers and Cell, 2017)
    Aim. To search for new CK2 inhibitors by virtual screening. Methods. Virtual screening of a small organic compounds library was performed by molecular docking using the Autodock 4.2.6 package and pharmacophore screening ...
  • Hit identification of FGFR1 inhibitors using receptor-based virtual screening 
    Tarnavskiy, S.S.; Protopopov, M.V.; Borovykov, O.V.; Pryhodko, A.O.; Bdzhola, V.G.; Yarmoluk, S.M. (Вiopolymers and Cell, 2019)
    Aim. To identify novel FGFR1 inhibitors using the virtual screening approach. Methods. Virtual screening of a small organic compounds library was performed by molecular docking using the Autodock 4.2.6 program package. The ...
  • Identification of 4‐methoxythieno[2,3‐d]pyrimidines as FGFR1 Inhibitors 
    Kotey, I.M.; Protopopov, M.V.; Starosyla, S.A.; Balanda, A.O.; Pletnova, L.V.; Prykhod'ko, A.O.; Bdzhola, V.G.; Yarmoluk, S.M. (Вiopolymers and Cell, 2019)
    Aim. To identify novel FGFR1 inhibitors using virtual screening approach. Methods. We used methods of organic synthesis, molecular docking via the Autodock 4.2.6 program package and in vitro biochemical tests with γ-32P. ...
  • Rational design of protein kinase inhibitors 
    Yarmoluk, S.M.; Nyporko, A.Yu.; Bdzhola, V.G. (Вiopolymers and Cell, 2013)
    Modern methodological approaches to rational design of low molecular weight compounds with specific activity in relation to predetermined biomolecular targets are considered by example of development of high effective ...
  • Synthesis and biological evaluation of novel amino-substituted derivatives of pyrido[2,3-d]pyrimidine as inhibitors of protein kinase CK2 
    Zinchenko, A.N.; Muzychka, L.V.; Smolii, O.B.; Bdzhola, V.G.; Protopopov, M.V.; Yarmoluk, S.M. (Вiopolymers and Cell, 2017)
    Aim. A search for human protein kinase CK2 inhibitors in a series of new amino-substituted pyrido[2,3-d]pyrimidine derivatives. Methods. Organic synthesis, analytical and spectral methods, molecular docking, in vitro ...

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