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Human papilloma virus and nasopharyngeal carcinoma: pathology, prognosis, recurrence and mortality of the disease

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dc.contributor.author Atighechi, S.
dc.contributor.author Mirvakili, S.A.
dc.contributor.author Sheikhha, M.H.
dc.contributor.author Baradaranfar, M.H.
dc.contributor.author Dadgarnia, M.H.
dc.contributor.author Behniafard, N.
dc.contributor.author Ahmadpour Baghdadabad, M.R.
dc.date.accessioned 2019-01-21T08:25:22Z
dc.date.available 2019-01-21T08:25:22Z
dc.date.issued 2014
dc.identifier.citation Human papilloma virus and nasopharyngeal carcinoma: pathology, prognosis, recurrence and mortality of the disease / S. Atighechi, M.R. Ahmadpour Baghdadabad, S.A. Mirvakili, M.H. Sheikhha, M.H. Baradaranfar, M.H. Dadgarnia, N. Behniafard // Experimental Oncology. — 2014. — Т. 36, № 3. — С. 215-216. — Бібліогр.: 12 назв. — англ. uk_UA
dc.identifier.issn 1812-9269
dc.identifier.uri http://dspace.nbuv.gov.ua/handle/123456789/145370
dc.description.abstract Background: One of the malignant tumors among head and neck cancers is nasopharyngeal carcinoma. Many studies consider human papilloma virus (HPV) as a cause for nasopharyngeal carcinoma. Methods: 41 paraffin-wax-embedded block samples were examined to detect HPV DNA and its subtype’s presence by polymerase chain reaction. The recurrence, prognosis and survival were evaluated for an average of 48 months. Results: HPV DNA was positive in 9 patients (22%). The overall recurrence rate was 75% in HPV negative patients and 11% in HPV positive ones. The mortality rate in HPV negative and positive patients was 37.5% and 0%, respectively. Conclusion: HPV type 18 and 16 were the most common subtypes. Also, it can be implied that patients which are HPV positive had better prognosis and also less recurrence. Key Words: human papilloma virus, nasopharyngeal cancer, polymerase chain reaction, prognosis, recurrence. uk_UA
dc.language.iso en uk_UA
dc.publisher Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України uk_UA
dc.relation.ispartof Experimental Oncology
dc.subject Short communications uk_UA
dc.title Human papilloma virus and nasopharyngeal carcinoma: pathology, prognosis, recurrence and mortality of the disease uk_UA
dc.type Article uk_UA
dc.status published earlier uk_UA


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