Наукова електронна бібліотека
періодичних видань НАН України
періодичних видань НАН України
Pristine C60 fullereneS inhibit the rate of tumor growth and metastasis
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| dc.contributor.author | Prylutska, S.V. | |
| dc.contributor.author | Burlaka, A.P. | |
| dc.contributor.author | Prylutskyy, Yu.I. | |
| dc.contributor.author | Ritter, U. | |
| dc.contributor.author | Scharff, P. | |
| dc.date.accessioned | 2018-06-19T10:47:06Z | |
| dc.date.available | 2018-06-19T10:47:06Z | |
| dc.date.issued | 2011 | |
| dc.identifier.citation | Pristine C60 fullereneS inhibit the rate of tumor growth and metastasis / S.V. Prylutska, A.P. Burlaka, Yu.I. Prylutskyy, U. Ritter, P. Scharff // Experimental Oncology. — 2011. — Т. 33, № 3. — С. 162-164. — Бібліогр.: 22 назв. — англ. | uk_UA |
| dc.identifier.issn | 1812-9269 | |
| dc.identifier.uri | http://dspace.nbuv.gov.ua/handle/123456789/138636 | |
| dc.description.abstract | Aim: To estimate the impact of C60 fullerene aqueous solution (C60FAS) on the rate of transplanted malignant tumor growth and metastasis. Methods: Lewis lung carcinoma was transplanted into С57Bl/6J male mice. Conventional methods for the evaluation of antitumor and antimetastatic effects have been used. Results: The C60FAS at low single therapeutic dose of 5 mg/kg inhibited the growth of transplanted malignant tumor (antitumor effect) and metastasis (antimetastatic effect): the maximum therapeutic effect was found to be of 76.5% for the tumor growth inhibition; the increase of animal life span by 22% was found; the metastasis inhibition index was estimated as 48%. Conclusion: It was found that water-soluble pristine С60 fullerenes efficiently inhibit the transplanted malignant tumor growth and metastasis. | uk_UA |
| dc.description.sponsorship | This work was partly supported by BMBF grant. | uk_UA |
| dc.language.iso | en | uk_UA |
| dc.publisher | Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України | uk_UA |
| dc.relation.ispartof | Experimental Oncology | |
| dc.subject | Short communications | uk_UA |
| dc.title | Pristine C60 fullereneS inhibit the rate of tumor growth and metastasis | uk_UA |
| dc.type | Article | uk_UA |
| dc.status | published earlier | uk_UA |
