Анотація:
Complex toxicological-hygienic studies of biodestructive bone miniplate samples for osteosynthesis composed of polyurethane co-polymer with epoxide hydroxyapatite and immunomodulator (levamisole-containing olygomer) are carried out. The results indicate the safety of the developed bone miniplate material, which allows us to recommend its usage as a fixing device for fractured bone fragments in oral and maxillofacial surgery.