Наукова електронна бібліотека
періодичних видань НАН України
періодичних видань НАН України
Role of dendrimers in advanced drug delivery and biomedical applications: a review
Репозиторій DSpace/Manakin
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Role of dendrimers in advanced drug delivery and biomedical applications: a review
Тема:
Reviews
Посилання:
Role of dendrimers in advanced drug delivery and biomedical applications: a review / A. Akbarzadeh, R. Khalilov, E. Mostafavi, N. Annabi, E. Abasi, T. Kafshdooz, R. Herizchi, T. Kavetskyy, S. Saghfi, A. Nasibova, S. Davaran // Experimental Oncology. — 2018 — Т. 40, № 3. — С. 178–183. — Бібліогр.: 91 назв. — англ.
Підтримка:
The authors thank the Department of Medical Nanotechnology, Faculty of Advanced Medical Science of Tabriz University, for all support provided. This work is funded by a 2017 grant by the Drug Applied Research Center, Tabriz University of Medical Sciences.
Дата:
2018
Переглядів:
1029
Завантажень:
738
Анотація:
Aim: Dendrimers dendritic structural design holds vast promises, predominantly for drug delivery, owing to their unique properties. Dendritic architecture is widespread topology found in nature and offers development of specific properties of chemical substances. Dendrimers are an ideal delivery vehicle candidate for open study of the effects of polymer size, charge, and composition on biologically relevant properties such as lipid bilayer interactions, cytotoxicity, bio-distribution, internalization, blood plasma retention time, and filtration. This article reviews role of dendrimers in advanced drug delivery and biomedical applications. Key Words: dendrimers, drug delivery vehicle, lipid bilayer interactions, dendritic architecture.
