Перегляд за автором "Pushkarev, V.M."

Результати 1-11 з 11

Apolipoprotein A1 level in plasma of patients with diabetes and diabetic patients with COVID-19 as a possible marker of disease

Tronko, M.D.; Cherviakova, S.A.; Pushkarev, V.V.; Belchina, Y.B.; Kovzun, O.I.; Pushkarev, V.M.; Sokolova, L.K. (Доповіді НАН України, 2021)

Increased levels of high-density lipoprotein cholesterol (HDL-C) and apolipoprotein A1 (ApoA1) in plasma is associated with a reduced risk of developing cardiovascular diseases (CVD). In addition to its potential ...
Apolipoprotein B and oxLDL levels in plasma of patients with diabetes, cardiovascular disease, and COVID-19

Tronko, M.D.; Cherviakova, S.A.; Pushkarev, V.V.; Belchina, Y.B.; Kovzun, O.I.; Pushkarev, V.M.; Sokolova, L.K. (Доповіді НАН України, 2021)

Elevated levels of low-density lipoprotein (LDL-X) cholesterol, apolipoprotein B (ApoB), and especially oxidized LDL in plasma are associated with an increased risk of cardiovascular disease (CVD). The aim of the study ...
Differential effects of low and high doses of taxol in anaplastic thyroid cancer cells: possible implication of the PIN1 prolyl isomerase

Pushkarev, V.M.; Starenki, D.V.; Saenko, V.A.; Pushkarev, V.V.; Kovzun, O.I.; Tronko, M.D.; Popadiuk, I.D.; Yamashita, S. (Experimental Oncology, 2008)

To study the molecular mechanisms of dose-dependent effects of an anticancer drug, Taxol, on the cell cycle machinery and apoptosis-related proteins in thyroid anaplastic cancer cell lines ARO and KTC-2. Materials and ...
Effect of combined treatment with insulin and metformin on 5′AMPactivated protein kinase activity in lymphocytes of diabetic patients

Sokolova, L.K.; Pushkarev, V.M.; Belchina, Y.B.; Pushkarev, V.V.; Tronko, M.D. (Доповіді НАН України, 2018)

The activity of 5′adenosine monophosphate-activated protein kinase (AMPK), controlling the energy balance of a cell, in blood cells at the combined treatment of patients with type 2 diabetes with metformin and insulin ...
Effect of combined treatment with insulin, metformin, and gliclazide on the expression and activity of Akt, mTOR, and p70S6K protein kinases in lymphocytes of diabetic patients

Sokolova, L.K.; Pushkarev, V.M.; Belchina, Yu.B.; Pushkarev, V.V.; Vatseba, T.S.; Tronko, M.D. (Доповіді НАН України, 2018)

The expression of the main effector protein kinase Akt of the PI3K signaling pathway and the activities of mTOR and p70S6K protein kinases in lymphocytes of patients with diabetes mellitus are determined at the ...
Effects of COVID-19 and diabetes mellitus on AMPKα1 and IRS-1 amount in the blood plasma of patients

Tronko, M.D.; Pushkarev, V.V.; Sokolova, L.K.; Cherviakova, S.A.; Belchina, Y.B.; Kovzun, O.I.; Guda, B.B.; Pushkarev, V.M. (Доповіді НАН України, 2022)

The aim of the study was to determine the levels of AMPKα1 and IRS-1 in the blood of patients with diabetes mellitus and COVID-19. AMPKα1 and IRS-1 were determined using enzyme-linked immunosorbent assay (ELISA) ...
Effects of COVID-19, diabetes mellitus, and cardiovascular diseases on insulin receptor substrate-1 amount in the blood plasma of patients

Tronko, M.D.; Pushkarev, V.V.; Sokolova, L.K.; Cherviakova, S.A.; Belchina, Yu.B.; Kovzun, O.I.; Pushkarev, V.M. (Доповіді НАН України, 2021)

Insulin receptor substrate (IRS) is a key adapter protein mediating effects of insulin and insulin-like growth factors (IGF) in cells. IRS-1 is a member of the insulin receptor substrate family, which is associated with ...
Effects of low and high concentrations of antitumour drug taxol in anaplastic thyroid cancer cells

Pushkarev, V.M.; Starenki, D.V.; Saenko, V.A.; Yamashita, S.; Kovzun, O.I.; Popadiuk, I.D.; Pushkarev, V.V.; Tronko, M.D. (Experimental Oncology, 2009)

Aim: To study the changes of cell cycle, mitochondrial membrane potential and caspase activation in response to an antitumour drug Taxol in ARO and KTC-2 cell lines of anaplastic thyroid carcinoma. Methods: Experiments ...
Effects of Paclitaxel and combination of the drug with radiation therapy in an in vivo model of anaplastic thyroid carcinoma

Pushkarev, V.M.; Starenki, D.V.; Saenko, V.O.; Tronko, M.D.; Yamashita, S. (Experimental Oncology, 2011)

Aim of this article is to study the effects of Paclitaxel (Ptx), γ-irradiation (IR) and their combination on the growth of xenografted tumors derived from undifferentiated thyroid cancer cells.
NT-proBNP blood levels in patients with type 2 diabetes mellitus with anemia and after the dapagliflozin treatment

Sokolova, L.K.; Pushkarev, V.M.; Belchina, Yu.B.; Pushkarev, V.V.; Furmanova, O.V.; Cherviakova, S.A.; Kovzun, O.I.; Tronko, M.D. (Доповіді НАН України, 2018)

The content of the brain natriuretic peptide (NT-proBNP) in blood plasma and the activity of 5′-adenosine monophosphate- activated protein kinase (AMPK) in lymphocytes of type 2 diabetes patients with anemia and after the ...
The effect of laser (384 nm) irradiation of the Lewis lung carcinoma on the tumor volume and the formation of metastases

Kanevskyi, V.A.; Osinskyi, S.P.; Pushkarev, V.M. (Доповіді НАН України, 2017)

We study the effect of laser irradiation upon implanted Lewis carcinoma. The irradiation of mice with Lewis carcinoma by a femtosecond pulsed laser with a wavelength of 384 nm was performed. Four groups of animals ...

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