Перегляд за автором "Kosach, V.R."

Результати 1-4 з 4

Characteristic of mTOR signaling and its involvement in the regulation of cell movements through remodeling the cytoskeleton architecture

Kosach, V.R.; Cherednyk, O.V.; Khoruzhenko, A.I. (2015)

mTOR kinase is one of the basic links at the crossroad of several signal transduction pathways. Deregulated mTOR kinase signaling accompanies the progress of cancer, diabetes, neurodegenerative disorders and aging. ...
Optimization of cell motility evaluation in scratch assay

Gotsulyak, N.Ya.; Kosach, V.R.; Cherednyk, O.V.; Tykhonkova, I.O.; Khoruzhenko, A.I. (Вiopolymers and Cell, 2014)

A scratch test is one of the most popular methods of classical cell migration assay in a monolayer culture. At the same time, the scratch assay has some disadvantages that can be easily corrected. Aim. Optimization the ...
Optimization of in vitro model for analysis of tumor cell migration dynamics

Kravchenko, A.O.; Kosach, V.R.; Shkarina, K.A.; Zaiets, I.V.; Tykhonkova, I.O.; Khoruzhenko, A.I. (Вiopolymers and Cell, 2018)

Migration ability is an important feature of tumor cells. There are several approaches to analyze the dynamics of cancer cell migration in vitro. One of the most perspective and closer to the in vivo conditions is the model ...
Phospho-mTOR (Ser2481) colocalizes with condensed chromosomes during metaphase

Kosach, V.R.; Tykhonkova, I.O.; Cherednyk, O.V.; Filonenko, V.V.; Khoruzhenko, A.I. (Вiopolymers and Cell, 2016)

Aim. To study the subcellular localization of phospho-mTOR (Ser2481) in cultured cells of human cancer cell lines. Methods. Immunofluorescent analysis of phospho-mTOR (Ser2481) subcellular localization in cultured MCF-7 ...

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Перегляд за автором "Kosach, V.R."

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