Перегляд за автором "Irodov, D.M."

Результати 1-7 з 7

Amazing MSC – phenomenology, problems, solutions and opportunities

Kordium, V.A.; Irodov, D.M. (Вiopolymers and Cell, 2017)

The review briefly describes the history of prediction and discovery of mesenchymal stem cells (MSCs). The evolution of our views on the nature, functions, and status of MSCs in the organism is presented. We propose that ...
Development of the chromatographic medium for the affinity isolation of the recombinant hIFN-β1b based on immobilized single-chain antibodies

Pokholenko, Ia.O.; Gorbatiuk, O.B.; Okunev, O.V.; Irodov, D.M.; Degtiarova, M.I.; Palivoda, O.G.; Kordium, V.A. (Вiopolymers and Cell, 2015)

Aim. The development of a laboratory method for the production of immunoaffinity chromatography medium for the purification of the recombinant human IFN-β1b. Methods. A gene of the chimeric protein ScFvbINF-CBD was constructed ...
Expression and secretion of human recombinant LIF by genetically modified mammalian cells

Rymar, S.Yu.; Ruban, T.A.; Irodov, D.M.; Kordium, V.A. (Вiopolymers and Cell, 2011)

Aim. The aim of this work was to express the human LIF gene in mammalian cells and to study the secretion of recombinant LIF into culture medium. Methods. Recombinant LIF was detected by Western blot analysis and ...
Fundamental gap in fundamental biology

Kordium, V.A.; Andrienko, V.I.; Maslova, O.A.; Shuvalova, N.S.; Irodov, D.M.; Ruban, T.A.; Sukhorada, E.M.; Likhacheva, L.I.; Shpilevaya, S.P. (Вiopolymers and Cell, 2011)

The article raises the problems of intracellular spatial and temporal organization of metabolism, signaling, and energy supply of these processes. To provide cell functions, the enzymes of metabolic chains, molecules of ...
Modelling of systemic lesion of organism for development of multitarget cellular and cytokine therapy

Kordium, V.A.; Chaikovsky, Yu.B.; Irodov, D.M.; Drahulian, M.V.; Gulko, T.P.; Buchek, P.V.; Korsak, A.V.; Neverovskiy, A.V. (Вiopolymers and Cell, 2016)

In recent decades many human pathologies have taken a chronic course. Modern biology and medicine have come to conceptually new therapeutic approaches. The technologies, comprising stem cells and signaling molecules, are ...
Recombinant Staphylococcal protein A with cysteine residue for preparation of affinity chromatography stationary phase and immunosensor applications

Gorbatiuk, O.B.; Bakhmachuk, A.O.; Dubey, L.V.; Usenko, M.O.; Irodov, D.M.; Okunev, O.V.; Kostenko, O.M.; Rachkov, A.E.; Kordium, V.A. (Вiopolymers and Cell, 2015)

Aim. Engineering of recombinant Staphylococcal protein A with cysteine residue (SPA-Cys) for preparation of affinity chromatography stationary phase and formation of bioselective element of immunosensor. Methods. DNA ...
Triggering effect of “therapeutic MSC”

Kordium, V.A.; Irodov, D.M.; Chaikovsky, Yu.B. (Вiopolymers and Cell, 2017)

The use of MSCs as a therapeutic agent is proven to be highly successful in many cases. However, the effects obtained are often temporary, and not leading to complete recovery. The reasons of such phenomenon are discussed ...

Результати 1-7 з 7

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Перегляд за автором "Irodov, D.M."

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