Перегляд за автором "Fedorchuk, A.G."

Результати 1-5 з 5

2-deoxy-D-glucose enhances dichloroacetate antitumor action against lewis lung carcinoma

Pyaskovskaya, O.N.; Kolesnik, D.L.; Fedorchuk, A.G.; Prochorova, I.V.; Solyanik, G.I. (Experimental Oncology, 2016)

Aerobic glycolysis that supports high proliferation rate and survival of tumor cells in unfavorable conditions is among fundamental features of tumor metabolism. The search for active modulators of energetic metabolism ...
Aconitine-containing agent enhances antitumor activity of dichloroacetate against Ehrlich carcinoma

Pyaskovskaya, O.N.; Boychuk, I.V.; Fedorchuk, A.G.; Kolesnik, D.L.; Dasyukevich, O.I.; Solyanik, G.I. (Experimental Oncology, 2015)

Significant variability of anticancer efficacy of dichloroacetate (DCA) stimulated an active search for the agents capable to enhance it antitumor action. Therefore, the aim of this work is the study of capability of ...
Circadian rhythms of cytotoxic activity in peripheral blood mononuclear cells of patients with malignant melanoma

Gamaleia, N.F.; Skivka, L.M.; Fedorchuk, A.G.; Shishko, E.D. (Experimental Oncology, 2006)

Aim: To study circadian rhythms (CR) of cytotoxic activity in peripheral blood mononuclear cells of patients with malignant melanoma were compared with those in healthy men. Methods: The NK-cell and phagocyte cytotoxic ...
Cytotoxic activity of metformin in vitro does not correlate with its antitumor action in vivo

Pyaskovskaya, O.N.; Kolesnik, D.L.; Fedorchuk, A.G.; Gorbik, G.V.; Solyanik, G.I. (Experimental Oncology, 2017)

It is known that metformin is a hypoglycemic drug used to treat type II diabetes mellitus. Recently active studies of its antitumor activity in relation to different types of malignant cells are conducted. Aim: To determine ...
Effectiveness of sodium dichloroacetate against glioma с6 depends on administration schedule and dosage

Fedorchuk, A.G.; Pyaskovskaya, O.N.; Gorbik, G.V.; Prokhorova, I.V.; Kolesnik, D.L.; Solyanik, G.I. (Experimental Oncology, 2016)

Background: Anticancer action of sodium dichloroacetate (DCA) could be related to its ability to activate oxidative phosphorylation leading to enhanced generation of reactive oxygen species and induction of apoptosis. On ...

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Перегляд за автором "Fedorchuk, A.G."

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