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Перегляд Experimental Oncology, 2012, № 1 за назвою

Репозиторій DSpace/Manakin

Перегляд Experimental Oncology, 2012, № 1 за назвою

Сортувати за: Порядок: Результатів:

  • Accelerated rejection of the second transplants of immunogenic tumor in mice under inhibition of indoleamine 2,3-dioxygenase activity by ethyl pyruvate 
    Vasilyeva, E.D.; Kaledin, V.; Nikolin, V.P.; Popova, N.A.; Kirilyuk, I.A.; Grigor`ev, I.A. (Experimental Oncology, 2012)
    Aim: A recently discovered enzyme, indoleamine 2,3-dioxygenase (IDO), is expressed in placenta, dendritic cells and also in many kinds of tumors and in tumor-infiltrating macrophages. By catabolizing tryptophan, IDO causes ...
  • Cancer with unknown primary: finding a needle in a hay stack 
    Giesel, F.L.; Mehndiratta, A.; Mafomane, M.P.; Zechmann, C.M.; Bergmann, F.; Schemmer, P.; Haberkorn, U.; Kratochwil, C. (Experimental Oncology, 2012)
    Detection and resection of small neuroendocrine tumours (NET) is like finding a needle in a hay stack. Use of specific tracers such as 68Ga-DOTATOC in a PET/CT study has been proven to have a high sensitivity and specificity ...
  • Gene expression profiling of B-CLL in Ukrainian patients in post-Chernobyl period 
    Savli, H.; Sunnetci, D.; Cine, N.; Gluzman, D.F.; Zavelevich, M.P.; Sklyarenko, L.M.; Nadgornaya, V.A.; Koval, S.V. (Experimental Oncology, 2012)
    Background: Genetic mechanisms that result in the development and progression of B-cell chronic lymphocytic leukemia (B-CLL) are mainly unknown. We have analyzed gene expression patterns in Ukrainian B-CLL patients with ...
  • Gold nanoparticles synthesis and biological activity estimation in vitro and in vivo 
    Rieznichenko, L.S.; Dybkova, S.M.; Gruzina, T.G.; Ulberg, Z.R.; Todor, I.N.; Lukyanova, N.Yu.; Shpyleva, S.I.; Chekhun, V.F. (Experimental Oncology, 2012)
    The aim of the work was the synthesis of gold nanoparticles (GNP) of different sizes and the estimation of their biological activity in vitro and in vivo. Materials and Methods: Water dispersions of gold nanoparticles of ...
  • Influence of surgical resection no plasma Endoglin (CD105) level in non-small cell lung cancer patients 
    Kopczynska, E.; Dancewicz, M.; Kowalewski, J.; Makarewicz, R.; Kardymowicz, H.; Kaczmarczyk, A.; Tyrakowski, T. (Experimental Oncology, 2012)
    Background and Aim: Endoglin is a proliferation-associated antigen on endothelial cells and essential for angiogenesis. Soluble endoglin (s‑endoglin), formed by proteolytic cleavage of ectodomain of membrane receptor could ...
  • Inhibition of TGFβ signaling and its implications in anticancer treatments 
    Calone, I.; Souchelnytskyi, S. (Experimental Oncology, 2012)
    The transforming growth factor-β (TGFβ) is a potent regulator of tumorigenesis. In cancer, two distinctive behaviors of TGFβ have been reported as a tumor suppressor at early stage of the disease, and as a tumor promoter ...
  • Metformin plus PIAF combination chemotherapy for hepatocellular carcinoma 
    Petrushev, B.; Tomuleasa, C.; Soritau, O.; Aldea, M.; Pop, T.; Susman, S.; Kacso, G.; Berindan, I.; Irimie, A.; Cristea, V. (Experimental Oncology, 2012)
    Objectives: Metformin, the most used oral antidiabetic drug for the treatment of type 2 diabetus mellitus, has proved encouraging results when used in the treatment of various types of cancer such as triple-negative breast ...
  • MicroRNAs and human cancer 
    Nikitina, E.G.; Urazova, L.N.; Stegny, V.N. (Experimental Oncology, 2012)
    MicroRNAs (miRNAs) are a recently discovered family of short non-coding RNA molecules of about 19–24 nucleotides in length that are involved in regulation of gene expression. These small molecules have been found to regulate ...
  • Novel germline MLH1 and MSH2 mutations in latvian Lynch syndrome families 
    Berzina, D.; Irmejs, A.; Kalniete, D.; Borosenko, V.; Nakazawa-Miklasevica, M.; Ribenieks, K.; Trofimovics, G.; Gardovskis, J.; Miklasevics, E. (Experimental Oncology, 2012)
    Background/Aims: Hereditary non-polyposis colorectal cancer or Lynch syndrome is an autosomal dominantly inherited disease with high penetrance, mostly due to mutations in the MLH1 and MSH2 genes. The aim of this study is ...
  • Polymorphisms of MTHFR and MTR genes are not related to susceptibility to childhood ALL in north India 
    Nikbakht, M.; MalekZadeh, K.; Kumar Jha, A.; Askari, M.; Marwaha, R.K.; Kaul, D.; Kaur, J. (Experimental Oncology, 2012)
    Background:Acute lymphoblastic leukemia (ALL) is the most worldwide common type of childhood cancer. Methylenetetrahydrofolate reductase (MTHFR) and 5-methyltetrahydrofolate-homocysteine methyltransferase (MTR) participate ...
  • Production of nitrogen oxide derivatives under the influence of NO-synthase inhibitors and natural compounds in mice with transplanted tumors 
    Deryagina, V.P.; Ryzhova, N.I.; Golubkina, N.A. (Experimental Oncology, 2012)
    Aim: The aim of the present study was to investigate the dynamics of nitric oxide derivative (NOD) formation in mice with transplanted tumors and to analize whether synthetic NO-synthase inhibitors, NO-donors and natural ...
  • Regulatory T cells but not NKT I cells are modulated by a single low-dose Cyclophosphamide in a B cell lymphoma tumor-model 
    Rico, M.J.; Rozados, V.R.; Mainetti, L.E.; Zacarias Fluck, M.F.; Matar, P.; Scharovsky, O.G. (Experimental Oncology, 2012)
    Aim: Experimental and clinical studies showed that the administration of cyclophosphamide (Cy) in low doses leads to an enhancement of the antitumor immune response. Our objective was to study the modulation, if any, by ...
  • The long-range cytotoxic effect in tumor-bearing animals 
    Gerashchenko, B.I.; Ryabchenko, N.M.; Glavin, O.A.; Mikhailenko, V.M. (Experimental Oncology, 2012)
    Aim:The relationship between cancer and patient health is still of great interest for experimental and clinical oncology. The tumor can adversely affect surrounding and distant tissues as well. However, effects of the tumor ...

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