Доповіді НАН України, 2008
http://dspace.nbuv.gov.ua:80/xmlui/handle/123456789/2907
2024-03-29T13:37:35ZМетодологические ограничения метода дерева событий
http://dspace.nbuv.gov.ua:80/xmlui/handle/123456789/7523
Методологические ограничения метода дерева событий
Пампуро, В.И.
A short analysis of the events tree method is given, and the theoretical groundlessness of the method is proved. The incorrectness to postulate a probabilistic model of accidents is shown. The error of accident risk assessments by the events tree method is determined.
2008-01-01T00:00:00ZАктивність Ca2+-залежних протеїнкіназ в епітеліоцитах слизової оболонки товстої кишки щурів за умов розвитку коліт-асоційованого канцерогенезу
http://dspace.nbuv.gov.ua:80/xmlui/handle/123456789/7522
Активність Ca2+-залежних протеїнкіназ в епітеліоцитах слизової оболонки товстої кишки щурів за умов розвитку коліт-асоційованого канцерогенезу
Кравченко, О.О.; Дробінська, О.В.; Остапченко, Л.І.
The free cytoplasmic Ca²^+ content and Ca²^+-dependent protein kinase activities are investigated in membrane and cytosolic fractions of rat colonocyte under the development of an experimental model of colitis-associated carcinogenesis. The increase of free endocellular Ca²^+ by 2 times as compared with control during the formation and development of colon inflammation is shown. It is established that enzymes of Ser-Thr phosphorilation mediate ulcerative colitis-associated carcinogenesis. These enzyme activities increase and reach their peak values in cytosol in the second week for protein kinase C, the fourth one for Ca/calmodulin-depenent kinase, and the tenth week in the membrane fraction.
2008-01-01T00:00:00ZРаспространение внехромосомных кольцевых ДНК у Erwinia carotovora
http://dspace.nbuv.gov.ua:80/xmlui/handle/123456789/7521
Распространение внехромосомных кольцевых ДНК у Erwinia carotovora
Сергеева, Ж.Ю.; Товкач, Ф.И.
The study of a plasmid composition of 54 Erwinia carotovora’s strains of different origins shows that 30% of these strains contain different extrachromosomal DNAs. These genetic elements belong to four discrete size classes. For the first time, the correlation of strains‘ plasmid maintenance and their belonging to a certain ecological niche is shown, and their sensibility to bacteriophages is studied. The restriction analysis of plasmids from the most widespread class detects a homology of E. carotovora’s extrachromosomal elements. Any correlation between strains‘ plasmid maintenance and the killer activity of carotovoricines of E. carotovora’s strains is not found.
2008-01-01T00:00:00ZВплив аутовакцини на основі пептидоглікану Staphylococcus аureus Wood 46 на динаміку росту експериментальних пухлин у мишей
http://dspace.nbuv.gov.ua:80/xmlui/handle/123456789/7520
Вплив аутовакцини на основі пептидоглікану Staphylococcus аureus Wood 46 на динаміку росту експериментальних пухлин у мишей
Позур, В.В.; Сківка, Л.М.; Потебня, Г.П.
The effect of peptidoglycan from Staphylococcus aureus Wood 46 and cancer autovaccine supplemented with PG on the growth of experimental tumors in mice is investigated. It is shown that bacterial peptidoglycan both alone and as a part of the cancer autovaccine inhibits the growth of tumors. The cancer autovaccine with PG had the most supressive effect on the Lewis lung carcinoma growth: tumor sizes in experimental animals were by 37% smaller than those in control.
2008-01-01T00:00:00Z