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Experimental Oncology, 2014 (том 36)
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Перегляд Experimental Oncology, 2014 (том 36) за назвою

Перегляд Experimental Oncology, 2014 (том 36) за назвою

Результати 33-52 з 57

Number of Langerhans cells is decreased in premalignant keratosis and skin cancers

Shevchuk, Z.; Filip, A.; Shevchuk, V.; Kashuba, E. (Experimental Oncology, 2014)

Background: It was shown earlier that a number of CD207 positive Langerhans cells was lower in basal cell carcinomas than in the normal epidermis. Moreover, benign skin lesions presented a higher number of Langerhans cells ...
Peculiarities of antioxidant system and iron metabolism in organism during development of tumor resistance to cisplatin

Chekhun, V.F.; Lozovska, Y.V.; Burlaka, A.P.; Lukyanova, N.Y.; Todor, I.N.; Naleskina, L.A. (Experimental Oncology, 2014)

Aim : To study in vivo the peculiarities of changes of iron metabolism and antioxidant system in dynamics of growth of Guerin carcinoma with different sensitivity to cisplatin. Materials and Methods: In order to evaluate ...
Photodynamic responsiveness of human leukemia Jurkat/A4 cells with multidrug resistant phenotype

Philchenkov, A.A.; Shishko, E.D.; Zavelevich, M.P.; Kuiava, L.M.; Miura, K.; Blokhin, D.Y.; Shton, I.O.; Gamaleia, N.F. (Experimental Oncology, 2014)

Photodynamic therapy (PDT) is considered as a possible alternative approach to overcoming multidrug resistance (MDR). Analysis of cross-resistance to PDT in cells with different MDR pathways and resistance levels seems to ...
Precision therapy to target apoptosis in prostate cancer

Kulik, G. (Experimental Oncology, 2014)

Androgen-independent prostate cancer shows limited response to existing systemic therapies. Recent advances in prostate-selective targeting of small molecule inhibitors and bacterial toxins have created opportunities to ...
Preclinical antitumor activity of the diindolylmethane formulation in xenograft mouse model of prostate cancer

Kiselev, V.I.; Drukh, V.M.; Muyzhnek, E.L.; Kuznetsov, I.N.; Pchelintseva, O.I.; Paltsev, M.A. (Experimental Oncology, 2014)

Aim: Preclinical study of the specific anticancer pharmacological activity of the formulation containing active substance 3,3ʹ-diindolylmethane (DIM), cod liver oil, polysorbate 80 and α-tocopherol acetate (vitamin E), in ...
Premorphological alterations in gastric mucosa in patients with gastric cancer: hypoxia level assessed by 31P NMR spectroscopy

Bubnovskaya, L.; Osinsky, D.; Trachevsky, V.; Naleskina, L.; Kovelskaya, A.; Gumenyuk, L. (Experimental Oncology, 2014)

The aim of this study was to detect the hypoxic status in adjacent histologically uninvolved gastric mucosa in gastric cancer (GC) patients. Patients and Methods: 50 naïve patients with primary GC, and one patient with ...
Reduced gene expression of bikunin as a prognostic marker for renal cell carcinoma

Bayraktar, E.; Igci, M.; Erturhan, S.; Igci, Y.Z.; Karakok, M.; Gogebakan, B.; Ulasli, M.; Cakmak, E.A.; Arslan, A. (Experimental Oncology, 2014)

Aim: Experimental and clinical studies showed that bikunin, a Kunitz-type protease inhibitor, found in urine and amniotic fluid has a role in spread of tumor cells by providing a significant reduction in the levels of ...
Risk assessment of cancer of the female reproductive system

Glushchenko, N.M.; Nesina, I.P.; Lurchenko, N.P.; Proskurnya, L.A.; Buchynska, L.G. (Experimental Oncology, 2014)

Aim: To create an information resource concerning multifactorial oncological diseases of the female reproductive system. Materials and Methods: A comprehensive search of the literature in the PubMed and Ukrainian scientific ...
Role of the hybrid Bcr/Abl kinase in the pathogenesis of chronic myeloid leukemia lacking C-Abl and CXCR4 proteins

Polishchuk, L.A.; Telegeev, G.D. (Experimental Oncology, 2014)

Philadelphia chromosome is a result of chromosomal rearrangement that leads to the appearing of the hybrid gene bcr/abl. A hybrid mRNA transcribes from bcr-promoter and many copies of hybrid molecules of Bcr/Abl protein ...
Significance of ferritin expression in formation of malignant phenotype of human breast cancer cells

Chekhun, S.V.; Lukyanova, N.Y.; Shvets, Y.V.; Burlaka, A.P.; Buchynska, L.G. (Experimental Oncology, 2014)

Aim: The aim of our study is to investigate the disorders of ferritin functioning in breast cancer (BC) cells of different molecular subtype. Materials and Methods: The cell lines used in the analysis include T47D, MCF-7, ...
Single dose regorafenib-induced hypertensive crisis

Yilmaz, B.; Kemal, Y.; Teker, F.; Kut, E.; Demirag, G.; Yucel, I. (Experimental Oncology, 2014)

Gastrointestinal stromal tumors (GISTs) are uncommon tumors of the gastrointestinal (GI) tract. Regorafenib is a new multikinase inhibitor and is approved for the treatment of GISTs in patients who develop resistance to ...
Subject Index to volume 36 (2014)

Автор відсутній (Experimental Oncology, 2014)
The anticancer efficiency of the xenogeneic vaccine and the indication for its use

Symchych, T.V.; Fedosova, N.I.; Karaman, O.M.; Yevstratieva, L.M.; Lisovenko, H.S.; Voyeykova, I.M.; Potebnia, H.P. (Experimental Oncology, 2014)

Aim: To investigate the anticancer efficiency of the xenogeneic vaccine in different tumor models and to assess the possibility whether level of antibodies (Ab) specific for vaccine’s proteins can be used as an indication ...
The characterization of IgG antibodies to GalNAc beta-terminated glycans of gastric cancer survivors

Smorodin, E.P.; Sergeyev, B.L.; Kurtenkov, O.A. (Experimental Oncology, 2014)

The elevated anti-GalNAcβ IgG level of serum was shown to be associated with the significantly better survival of patients with gastrointestinal cancer. Aim: To characterize the specificity of IgG antibodies to GalNAcβ-terminated ...
The frequency of human papilloma virus types 16, 18 in upper genital tract of women at high risk of developing ovarian cancer

Bilyk, O.O.; Pande, N.T.; Pejovic, T.; Buchynska, L.G. (Experimental Oncology, 2014)

Aim: To investigate the incidence of human papilloma virus (HPV) types 16, 18 in upper genital tract of women considered at a high risk (HR) of developing epithelial ovarian cancer (EOC). Methods: HPV 16 and 18 E6 ORF ...
The influence of 5-fluorouracil on activity of thymidine phosphorylase in gastric adenocarcinoma and normal adjacent tissue

Stashkevych, M.; Khomutov, E.; Dumanskiy, Y.; Matviyenko, A.; Zinkovych, I. (Experimental Oncology, 2014)

The aim of the present study was to evaluate the change of thymidine phosphorylase (TP) activity in gastric adenocarcinoma and adjacent tissue upon the intraarterial administration of 5-fluorouracil (5-FU). Matherials and ...
The influence of enterosorption on some haematological and biochemical indices of the normal rats after single injection of melphalan

Shevchuk, O.O.; Posokhova, К.А.; Sidorenko, A.S.; Bardakhivska, К.І.; Maslenny, V.M.; Yushko, L.A.; Chekhun, V.F.; Nikolaev, V.G. (Experimental Oncology, 2014)

Aim: One of the most prominent side effects of intensive cancer chemotherapy is bone marrow suppression which is an independent negative prognostic factor for the time to tumor progression. The aim of the study was to ...
The phenomenon of multi-drug resistance in the treatment of malignant tumors

Vtorushin, S.V.; Khristenko, K.Y.; Zavyalova, M.V.; Perelmuter, V.M.; Litviakov, N.V.; Denisov, E.V.; Dulesova, A.Y.; Cherdyntseva, N.V. (Experimental Oncology, 2014)

Multi-drug resistance (MDR) is a condition when there is broad cross-resistance of cells to various agents which are different in structure and effect. Modern perceptions on mechanisms of MDR development in malignant tumors ...
The phospho-c-JUN (Ser63) content in mucosa cells under experimental development of gastric cancer

Tymoshenko, M.O.; Kravchenko, O.O.; Sokur, O.V.; Ostapchenko, L.I. (Experimental Oncology, 2014)

Aim: The aim of the study was to determine the phosphorylated c-Jun content and reduced and oxidized glutathione (GSH/GSSG) ratio in gastric mucosa cells during the process of gastric cancer development in rats. Materials ...
The role of nt590 P21 gene polymorphism in the susceptibility to nasopharyngeal cancer

Soares, S.; Catarino, R.; Breda, E.; Medeiros, R.; Bravo, I. (Experimental Oncology, 2014)

Aim: The purpose of this study was to assess if the P21 nt590 polymorphism is associated with the susceptibility to nasopharyngeal cancer and with the age at diagnosis. Materials and Methods: We analyzed the frequency of ...

Результати 33-52 з 57

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Перегляд Experimental Oncology, 2014 (том 36) за назвою

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Перегляд Experimental Oncology, 2014 (том 36) за назвою

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