Перегляд за автором "Macewicz, L.L."

Результати 1-8 з 8

A link between β-catenin and hypertrophy: evaluation and meta-analysis

Palchevska, O.L.; Macewicz, L.L.; Piven, O.O. (Вiopolymers and Cell, 2016)

Heart is a terminally differentiated organ almost unable to regenerate. The remodeling and hypertrophic growth are believed to be the main mechanisms of heart renovation after workloads or injury. Although there have been ...
Cardiospecific knockout of αE-catenin leads to violation of the neonatal cardiomyocytes maturation via β-catenin and Yap signaling

Balatskyi, V.V.; Ruban, T.P.; Macewicz, L.L.; Piven, O.O. (Вiopolymers and Cell, 2017)

Aim. To study the αE-catenin gene function in neonatal cardiomyocytes proliferation and matura-tion. Methods. Conditional knockout approach, histological (H&E and acridine orange staining) and molecular genetics (qPCR) ...
Correlation of mutagenesis level with expression of reparative enzyme O6-methylguanine DNA methyltransferase during establishment of cell lines in vitro

Macewicz, L.L.; Kushniruk, V.O.; Iatsyshyna, A.P.; Kotsarenko, K.V.; Lylo, V.V.; Akopyan, G.R.; Huleuk, N.L.; Mykytenko, D.O.; Lukash, L.L. (Вiopolymers and Cell, 2013)

Long-term cultivation of cell lines inevitably leads to genetic and epigenetic changes. The aim of this work was a comparative analysis of karyotype and level of the expression of reparative enzyme O6-methylguanine-DNA- ...
Embryonically induced β-catenin haploinsufficiency attenuates postnatal heart development and causes violation of foetal genes program

Palchevska, O.L.; Balatskii, V.V.; Andrejeva, A.O.; Macewicz, L.L.; Piven, O.O.; Lukash, L.L. (Вiopolymers and Cell, 2013)

The β-catenin role in myocardium remodeling and hypertrophy development is the subject of numerous and controversial investigations. Aim. To investigate the significance of cardiac ablation of β-catenin for heart development ...
Influence of EMAP II, IFN-α2b and its medicinal preparations on the MGMT protein amount in human cells in vitro

Kotsarenko, K.V.; Lylo, V.V.; Ruban, T.P.; Macewicz, L.L.; Kornelyuk, A.I.; Chernykh, S.I.; Lukash, L.L. (Вiopolymers and Cell, 2014)

Aim. To study the effect of EMAP II, IFN-α2b and its medicinal preparations on the amount of O6-methylguanine-DNA methyltransferase (MGMT) protein in human cells in vitro. Methods. The human cells of 4BL and Hep-2 lines ...
Influence of some biologically active substances on amount of MGMT and MARP proteins in human cells in vitro

Kotsarenko, K.V.; Lylo, V.V.; Macewicz, L.L.; Ruban, T.P.; Luchakivska, Yu.S.; Kuchuk, M.V.; Lukash, L.L. (Вiopolymers and Cell, 2014)

Aim. To investigate an effect of biologically active compounds IFN-α2b, EMAPII, Card medium, fibronectin on the amount of MGMT (O6-methylguanine-DNA methyltransferase) and MARP (anti-Methyltransferase Antibody ...
Isolectins from Sambucus nigra fl owers and their effect on MGMT and P53 proteins amount in human cells in vitro

Lylo, V.V.; Karpova, I.S.; Kotsarenko, K.V.; Macewicz, L.L.; Ruban, T.A.; Dziuba, G.V.; Lukash, L.L. (Фактори експериментальної еволюції організмів, 2015)

Aim. To characterise S.nigra fl ower isolectins in the aspect of their effect on MGMT and p53 proteins amount. Methods. Lectin preparations P1, P2 and P3 with defferent pI were obtained by isoelectric focusing. The Hep-2 ...
Plant and animal lectines as modulators of mgmt and marp gene expression in vitro

Macewicz, L.L.; Lylo, V.V.; Karpova, I.S.; Kotsarenko, K.V.; Ruban, T.A.; Lukash, L.L. (Фактори експериментальної еволюції організмів, 2014)

Aims. Previously for the first time we have studied the ability of lectins to influence the processes of mutagenesis and antimutagenesis in different test systems. The aim of present study was to examine the effect of panel ...

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Перегляд за автором "Macewicz, L.L."

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