Перегляд за автором "Cherdyntseva, N.V."

Результати 1-7 з 7

Age-related function of tumor suppressor gene TP53:contribution to cancer risk and progression

Cherdyntseva, N.V.; Gervas, P.A.; Litvyakov, N.V.; Stakcheeva, M.N.; Ponomaryeva, A.A.; Dobrodeev, A.Yu.; Denisov, E.V.; Belyavskaya, V.A.; Choinzonov, E.L. (Experimental Oncology, 2010)

Aim: To examine the influence of combined genotypes of TP53 (exon 4, intron 3, intron 6) and XRCC1 (codon 10) on lung cancer age of onset. Methods: TP53 polymorphisms in codon 72 of exon 4 (Arg72Pro), in intron 3 (16 bp ...
Circulating tumor cells in breast cancer: functional heterogeneity, pathogenetic and clinical aspects

Cherdyntseva, N.V.; Litviakov, N.V.; Denisov, E.V.; Gervas, P.A.; Cherdyntsev, E.S. (Experimental Oncology, 2017)

Each patient has a unique history of cancer ecosystem development, resulting in intratumor heterogeneity. In order to effectively kill the tumor cells by chemotherapy, dynamic monitoring of driver molecular alterations is ...
Different morphological structures of breast tumors demonstrate individual drug resistance gene expression profiles

Gerashchenko, T.S.; Denisov, E.V.; Novikov, N.M.; Tashireva, L.A.; Kaigorodova, E.V.; Savelieva, O.E.; Zavyalova, M.V.; Cherdyntseva, N.V.; Perelmuter, V.M. (Experimental Oncology, 2018)

Aim: To identify gene expression profiles involved in drug resistance of different morphological structures (tubular, alveolar, solid, trabecular, and discrete) presented in breast cancer. Material and Methods: Ten patients ...
Different morphological structures of breast tumors demonstrate individual drug resistance gene expression profiles

Gerashchenko, T.S.; Denisov, E.V.; Novikov, N.M.; Tashireva, L.A.; Kaigorodova, E.V.; Savelieva, O.E.; Zavyalova, M.V.; Cherdyntseva, N.V.; Perelmuter, V.M. (Experimental Oncology, 2018)

Aim: To identify gene expression profiles involved in drug resistance of different morphological structures (tubular, alveolar, solid, trabecular, and discrete) presented in breast cancer. Material and Methods: Ten patients ...
Genome-wide association study of loss of heterozygosity and metastasis-free survival in breast cancer patients

Deryusheva, I.V.; Tsyganov, M.M.; Garbukov, E.Y.; Ibragimova, M.K.; Kzhyshkovska, Ju.G.; Slonimskaya, E.M.; Cherdyntseva, N.V.; Litviakov, N.V. (Experimental Oncology, 2017)

One of the factors providing the diversity and heterogeneity of malignant tumors, particularly breast cancer, are genetic variations, due to gene polymorphism, and, especially, the phenomenon of loss of heterozygosity ...
Smoking-related DNA adducts as potential diagnostic markers of lung cancer: new perspectives

Grigoryeva, E.S.; Kokova, D.A.; Gratchev, A.N.; Cherdyntsev, E.S.; Buldakov, M.A.; Kzhyshkowska, J.G.; Cherdyntseva, N.V. (Experimental Oncology, 2015)

In recent years, the new direction such as identification of informative circulating markers reflecting molecular genetic changes in the DNA of tumor cells was actively developed. Smoking-related DNA adducts are very ...
The phenomenon of multi-drug resistance in the treatment of malignant tumors

Vtorushin, S.V.; Khristenko, K.Y.; Zavyalova, M.V.; Perelmuter, V.M.; Litviakov, N.V.; Denisov, E.V.; Dulesova, A.Y.; Cherdyntseva, N.V. (Experimental Oncology, 2014)

Multi-drug resistance (MDR) is a condition when there is broad cross-resistance of cells to various agents which are different in structure and effect. Modern perceptions on mechanisms of MDR development in malignant tumors ...

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Перегляд за автором "Cherdyntseva, N.V."

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