Перегляд за темою "Short Communications"

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  • RTK signaling regulator SPRY2 associates with endocytic adaptor ITSN1 in vivo 
    Novokhatska, O.V.; Skrypkina, I.Ya.; Dergai, M.V.; Tsyba, L.O.; Rynditch, A.V. (Вiopolymers and Cell, 2012)
    Передача митогенного сигнала от RTK (рецепторных тирозиновых киназ) тесно связана с эндоцитозом, регулирующим ее точность. Интерсектин 1 (ITSN1) – эволюционно-консервативный адапторный белок, вовлеченный в самые ранние ...
  • Specificity of DNA import into isolated mitochondria from plants and mammals 
    Koulintchenko, M.V.; Ibrahim, N.; Klimenko, E.S.; Konstantinov, Yu.M.; Weber-Lotfi, F.; Dietrich, A. (Вiopolymers and Cell, 2014)
    Aim. Investigation of different features of DNA import into plant and human mitochondria, for a better understanding of mitochondrial genetics and generation of biotechnological tools. Methods. DNA up-take experiments with ...
  • Study on the IFNL4 gene ss469415590 variant in Ukrainian population 
    Kucherenko, A.M.; Pampukha, V.M.; Livshits, L.A. (Вiopolymers and Cell, 2014)
    Aim. To determine genotype and allele disribution for the IFNL4 gene ss469415590 and examine it for linkage with the IL28B gene rs12979860 in Ukrainian population. Methods. The studied group consisted of 100 unrelated ...
  • Telomerase inhibition by new di- and trisubstituted acridine derivatives 
    Negrutska, V.V.; Saraieva, I.V.; Kostina, V.G.; Alexeeva, I.V.; Lysenko, N.A.; Dubey, I.Ya. (Вiopolymers and Cell, 2016)
    Aim. To study a series of new acridine derivatives containing two basic fragments able to bind to quadruplex DNA at C-4 and C-9 positions as potential telomerase inhibitors. Methods. TRAP assay was used to determine the ...
  • The accumulation of the basic domain of HIV-1 Tat protein in the nuclei and the nucleoli is different from the accumulation of full-length Tat proteins 
    Musinova, Y.R.; Sheval, E.V. (Вiopolymers and Cell, 2015)
    Aim. Protein fragments coding for nuclear (NLS) and/or nucleolar (NoLS) localization signals are often used for the investigation of the mechanisms of protein accumulation inside the nuclei and the nucleoli, but it is ...
  • The level of blood plasma mitochondrial DNA upon acute myocardium damage in experiment 
    Sudakov, N.P.; Popkova, T.P.; Novikova, M.A.; Katyshev, A.I.; Nikiforov, S.B.; Pushkarev, B.G.; Goldberg, O.A.; Klimenkov, I.B.; Lepekhova, S.A.; Ezhikeeva, S.D.; Ten, M.N.; Osipov, V.G.; Konstantinov, Yu.M. (Вiopolymers and Cell, 2012)
    The aim of the present investigation is to study the level of plasma mtDNA as a potential marker of cardiomyocyte damage in 2 and 4 h after subcutaneous injection of adrenaline and during the formed morphological alterations ...
  • Клонирование и экспрессия гена SPAА Еrysipelothrix rhusiopathiae в Еscherichia coli 
    Дерябин, О.Н.; Дерябина, Е.Г.; Гильчук, П.В. (Вiopolymers and Cell, 2011)
    Цель. Клонировать ген SPAА – поверхностный антиген Er. rhusiopathiae – в плазмидный вектор и экспрессировать белок SpaА в E. coli. Методы. Расчет и синтез олигонуклеотидных праймеров, полиме - разная цепная реакция, ...